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Sköpunargáfa (1)View MoreJournalNature neuroscience (1)Authors[ 1 ] deCODE Genet Amgen, Reykjavik, Iceland [ 2 ] Kings Coll London, Inst Psychiat, Genet & Dev Psychiat Ctr, MRC Social, London WC2R 2LS, England [ 3 ] Erasmus Univ, Erasmus Sch Econ, Rotterdam, Netherlands [ 4 ] Vrije Univ Amsterdam, Dept Biol Psychol, Netherlands Twin Register, Amsterdam, Netherlands [ 5 ] Stockholm Sch Econ, Dept Econ, Stockholm, Sweden [ 6 ] Radboud Univ Nijmegen, Med Ctr, Radboud Inst Hlth Sci, Nijmegen, Netherlands [ 7 ] Ctr Expt Social Sci, New York, NY USA [ 8 ] Univ So Calif, Ctr Econ & Social Res, Los Angeles, CA USA [ 9 ] Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden [ 10 ] Karolinska Inst, Dept Neurosci, Stockholm, Sweden [ 11 ] Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands [ 12 ] Landspitali Univ Hosp, Dept Psychiat, Reykjavik, Iceland [ 13 ] Univ Iceland, Dept Anthropol, Reykjavik, Iceland [ 14 ] Univ Amsterdam, Fac Econ & Business, Amsterdam, Netherlands (1)Abdellaoui, Abdel (1)Benjamin, Daniel J (1)Bjornsdottir, Gyda (1)Boomsma, Dorret I (1)View MoreTypes
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Polygenic risk scores for schizophrenia and bipolar disorder predict creativity.

Power, Robert A; Steinberg, Stacy; Bjornsdottir, Gyda; Rietveld, Cornelius A; Abdellaoui, Abdel; Nivard, Michel M; Johannesson, Magnus; Galesloot, Tessel E; Hottenga, Jouke J; Willemsen, Gonneke; et al. (Nature Publishing Group, 2015-07)
We tested whether polygenic risk scores for schizophrenia and bipolar disorder would predict creativity. Higher scores were associated with artistic society membership or creative profession in both Icelandic (P = 5.2 × 10(-6) and 3.8 × 10(-6) for schizophrenia and bipolar disorder scores, respectively) and replication cohorts (P = 0.0021 and 0.00086). This could not be accounted for by increased relatedness between creative individuals and those with psychoses, indicating that creativity and psychosis share genetic roots.
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