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dc.contributor.authorZoëga, Sigridur
dc.contributor.authorFridriksdottir, Nanna
dc.contributor.authorSigurdardottir, Valgerdur
dc.contributor.authorGunnarsdottir, Sigridur
dc.date.accessioned2014-05-26T14:03:12Z
dc.date.available2014-05-26T14:03:12Z
dc.date.issued2013-08
dc.date.submitted2014-05-26
dc.identifier.citationQual Life Res 2013, 22(6):1273-80en
dc.identifier.issn1573-2649
dc.identifier.pmid22975925
dc.identifier.doi10.1007/s11136-012-0264-x
dc.identifier.urihttp://hdl.handle.net/2336/317474
dc.descriptionTo access publisher's full text version of this article. Please click on the hyperlink in Additional Links field.en
dc.description.abstractThe purpose of this study was to assess pain, other symptoms and QOL, and the relationship between these variables, among cancer patients on strong opioids.
dc.description.abstractThe study was cross-sectional, descriptive, and correlational. A convenience sample of 150 cancer patients, ≥18 years, all on strong opioids for ≥ 3 days was recruited.
dc.description.abstractThe mean (SD) age was 64.7 (12.7) years, and 59 % were women. Mean (SD) time from cancer diagnosis was 36.3 (55.1) months. The median number of symptoms was 9, range 1-16 and the mean (SD) severity was 1.9 (0.5) on a 1-4 scale. Pain was one of the most prevalent (90 %) and severe symptoms with a mean (SD) of 2.56 (0.9). Number of symptoms explained 25.8 % of the variance in QOL, adjusted for age and sex. Another model, also adjusted for age and sex, showed that pain, fatigue, insomnia and depression, explained 33.6 % of the variance in QOL.
dc.description.abstractThe symptomatology in this study was similar to studies on patients with advanced cancer. QOL was associated with the number of symptoms patients experience and individual symptoms, notably fatigue and pain. Despite the use of strong opioids, pain was both common and severe, suggesting under-treatment. Pain and other symptoms need to be assessed and managed in order to improve patients' QOL. Special attention needs to be paid to multisymptom management in patients on opioids.
dc.description.sponsorshipIcelandic Research Fund for Graduate Students University of Iceland Landspitali University Hospital Research Fund Icelandic Nurses Association Icelandic Cancer Society Bergpora Magnusdottir and Jakob J. Bjarnason Memorial Fund Palliative Unit at the Landspitali University Hospital Oncology Unit of the Landspitali University Hospitalen
dc.language.isoenen
dc.publisherSpringer Internationalen
dc.relation.urlhttp://dx.doi.org/10.1007/s11136-012-0264-xen
dc.relation.urlhttp://link.springer.com/article/10.1007%2Fs11136-012-0264-xen
dc.rightsArchived with thanks to Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitationen
dc.subject.meshAdulten
dc.subject.meshAgeden
dc.subject.meshAnalgesics, Opioiden
dc.subject.meshCross-Sectional Studiesen
dc.subject.meshDepressionen
dc.subject.meshFatigueen
dc.subject.meshFemaleen
dc.subject.meshHumansen
dc.subject.meshLogistic Modelsen
dc.subject.meshMaleen
dc.subject.meshMiddle Ageden
dc.subject.meshNeoplasmsen
dc.subject.meshPainen
dc.subject.meshPrevalenceen
dc.subject.meshQuality of Lifeen
dc.subject.meshQuestionnairesen
dc.subject.meshSickness Impact Profileen
dc.subject.meshSocioeconomic Factorsen
dc.subject.meshSurvivorsen
dc.titlePain and other symptoms and their relationship to quality of life in cancer patients on opioids.en
dc.typeArticleen
dc.contributor.departmentNatl Univ Hosp Iceland, Landspitali, IS-101 Reykjavik, Iceland, Univ Iceland, Reykjavik, Icelanden
dc.identifier.journalQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitationen
dc.rights.accessNational Consortium - Landsaðganguren
html.description.abstractThe purpose of this study was to assess pain, other symptoms and QOL, and the relationship between these variables, among cancer patients on strong opioids.
html.description.abstractThe study was cross-sectional, descriptive, and correlational. A convenience sample of 150 cancer patients, ≥18 years, all on strong opioids for ≥ 3 days was recruited.
html.description.abstractThe mean (SD) age was 64.7 (12.7) years, and 59 % were women. Mean (SD) time from cancer diagnosis was 36.3 (55.1) months. The median number of symptoms was 9, range 1-16 and the mean (SD) severity was 1.9 (0.5) on a 1-4 scale. Pain was one of the most prevalent (90 %) and severe symptoms with a mean (SD) of 2.56 (0.9). Number of symptoms explained 25.8 % of the variance in QOL, adjusted for age and sex. Another model, also adjusted for age and sex, showed that pain, fatigue, insomnia and depression, explained 33.6 % of the variance in QOL.
html.description.abstractThe symptomatology in this study was similar to studies on patients with advanced cancer. QOL was associated with the number of symptoms patients experience and individual symptoms, notably fatigue and pain. Despite the use of strong opioids, pain was both common and severe, suggesting under-treatment. Pain and other symptoms need to be assessed and managed in order to improve patients' QOL. Special attention needs to be paid to multisymptom management in patients on opioids.


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