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dc.contributor.authorRytter, Dorte
dc.contributor.authorBech, Bodil H
dc.contributor.authorHalldorsson, Thorhallur
dc.contributor.authorChristensen, Jeppe H
dc.contributor.authorSchmidt, Erik B
dc.contributor.authorDanielsen, Inge
dc.contributor.authorHenriksen, Tine B
dc.contributor.authorOlsen, Sjurdur F
dc.date.accessioned2014-08-05T15:49:29Z
dc.date.available2014-08-05T15:49:29Z
dc.date.issued2013-12-14
dc.date.submitted2013
dc.identifier.citationBr. J. Nutr. 2013, 110 (11):2037-46en
dc.identifier.issn1475-2662
dc.identifier.pmid23680230
dc.identifier.doi10.1017/S0007114513001335
dc.identifier.urihttp://hdl.handle.net/2336/324283
dc.descriptionTo access publisher's full text version of this article click on the hyperlink at the bottom of the pageen
dc.description.abstractThe intake of marine n-3 PUFA has been shown to decrease the risk of CVD in a number of studies. Since the development of CVD is often a lifelong process, marine n-3 PUFA intake early in life may also affect the development of later CVD. The aim of the present study was to investigate the association between maternal intake of marine n-3 PUFA during the second trimester of pregnancy and factors associated with cardiometabolic risk in the 20-year-old offspring. The study was based on the follow-up of the offspring of a Danish pregnancy cohort who participated in a study conducted from 1988 to 1989. A total of 965 pregnant women were originally included in the cohort and detailed information about the intake of marine n-3 PUFA during the second trimester was collected. In 2008-9, the offspring were invited to participate in a clinical examination including anthropometric, blood pressure (BP) and short-term heart rate variability measurements. Also, a fasting venous blood sample was drawn from them. Multiple linear regression modelling, using the lowest quintile of marine n-3 PUFA intake as the reference, was used to estimate the association with all outcomes. A total of 443 offspring participated in the clinical examination. No association between the intake of marine n-3 PUFA during the second trimester of pregnancy and offspring adiposity, glucose metabolism, BP or lipid profile was found. In conclusion, no association between the intake of marine n-3 PUFA during the second trimester of pregnancy and the factors associated with cardiometabolic risk in the 20-year-old offspring could be detected.
dc.description.sponsorshipDanish Council for Strategic Research 09-067124 2101-07-0025 2101-06-0005en
dc.language.isoenen
dc.publisherCambridge Univ Pressen
dc.relation.urlhttp://dx.doi.org/10.1017/S0007114513001335en
dc.relation.urlhttp://journals.cambridge.org/download.php?file=%2FBJN%2FBJN110_11%2FS0007114513001335a.pdf&code=ad624accde1480cd9ea5e022a6df2e32en
dc.rightsArchived with thanks to The British journal of nutritionen
dc.subjectOffitaen
dc.subjectFæðubótarefnien
dc.subjectMeðgangaen
dc.subjectHáþrýstinguren
dc.subjectKransæðasjúkdómaren
dc.subjectMataræðien
dc.subjectSjávarfangen
dc.subject.meshAdulten
dc.subject.meshAquatic Organismsen
dc.subject.meshBody Mass Indexen
dc.subject.meshCardiovascular Diseasesen
dc.subject.meshCohort Studiesen
dc.subject.meshDenmarken
dc.subject.meshDietary Supplementsen
dc.subject.meshDyslipidemiasen
dc.subject.meshFatty Acids, Omega-3en
dc.subject.meshFemaleen
dc.subject.meshFollow-Up Studiesen
dc.subject.meshGlucose Metabolism Disordersen
dc.subject.meshHumansen
dc.subject.meshHypertensionen
dc.subject.meshMaleen
dc.subject.meshMaternal Nutritional Physiological Phenomenaen
dc.subject.meshOverweighten
dc.subject.meshPregnancyen
dc.subject.meshPregnancy Trimester, Seconden
dc.subject.meshPrevalenceen
dc.subject.meshRisk Factorsen
dc.subject.meshSeafooden
dc.subject.meshYoung Adulten
dc.titleNo association between the intake of marine n-3 PUFA during the second trimester of pregnancy and factors associated with cardiometabolic risk in the 20-year-old offspring.en
dc.typeArticleen
dc.contributor.departmentAarhus Univ, Dept Publ Hlth, Epidemiol Sect, DK-8000 Aarhus C, Denmark, Statens Serum Inst, Ctr Fetal Programming, Dept Epidemiol Res, DK-2300 Copenhagen, Denmark, Univ Iceland, Fac Food Sci & Nutr, Reykjavik, Iceland, Landspitali Univ Hosp, Unit Nutr Res, Reykjavik, Iceland, Aarhus Univ Hosp, Aalborg Hosp, Dept Nephrol, Aalborg, Denmark, Aarhus Univ Hosp, Aalborg Hosp, Ctr Cardiovasc Dis, Aalborg, Denmark, Aarhus Univ Hosp, Aalborg Hosp, Dept Cardiol, Aalborg, Denmark, Aarhus Univ Hosp, Skejby Hosp, Dept Pediat, DK-8000 Aarhus, Denmarken
dc.identifier.journalThe British journal of nutritionen
dc.rights.accessNational Consortium - Landsaðganguren
html.description.abstractThe intake of marine n-3 PUFA has been shown to decrease the risk of CVD in a number of studies. Since the development of CVD is often a lifelong process, marine n-3 PUFA intake early in life may also affect the development of later CVD. The aim of the present study was to investigate the association between maternal intake of marine n-3 PUFA during the second trimester of pregnancy and factors associated with cardiometabolic risk in the 20-year-old offspring. The study was based on the follow-up of the offspring of a Danish pregnancy cohort who participated in a study conducted from 1988 to 1989. A total of 965 pregnant women were originally included in the cohort and detailed information about the intake of marine n-3 PUFA during the second trimester was collected. In 2008-9, the offspring were invited to participate in a clinical examination including anthropometric, blood pressure (BP) and short-term heart rate variability measurements. Also, a fasting venous blood sample was drawn from them. Multiple linear regression modelling, using the lowest quintile of marine n-3 PUFA intake as the reference, was used to estimate the association with all outcomes. A total of 443 offspring participated in the clinical examination. No association between the intake of marine n-3 PUFA during the second trimester of pregnancy and offspring adiposity, glucose metabolism, BP or lipid profile was found. In conclusion, no association between the intake of marine n-3 PUFA during the second trimester of pregnancy and the factors associated with cardiometabolic risk in the 20-year-old offspring could be detected.


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