Consumption of fish products across the lifespan and prostate cancer risk.
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Your vote was cast
Thank you for your feedback
Thank you for your feedback
AuthorsTorfadottir, Johanna E
Valdimarsdottir, Unnur A
Mucci, Lorelei A
Kasperzyk, Julie L
Harris, Tamara B
MetadataShow full item record
CitationPLoS ONE 2013, 8 (4):e59799
ÚtdrátturTo examine whether fish and fish oil consumption across the lifespan is associated with a lower risk of prostate cancer.
The study was nested among 2268 men aged 67-96 years in the AGES-Reykjavik cohort study. In 2002 to 2006, dietary habits were assessed, for early life, midlife and later life using a validated food frequency questionnaire. Participants were followed for prostate cancer diagnosis and mortality through 2009 via linkage to nationwide cancer- and mortality registers. Adjusting for potential confounders, we used regression models to estimate odds ratios (ORs) and hazard ratios (HRs) for prostate cancer according to fish and fish oil consumption.
Among the 2268 men, we ascertained 214 prevalent and 133 incident prostate cancer cases, of which 63 had advanced disease. High fish consumption in early- and midlife was not associated with overall or advanced prostate cancer. High intake of salted or smoked fish was associated with a 2-fold increased risk of advanced prostate cancer both in early life (95% CI: 1.08, 3.62) and in later life (95% CI: 1.04, 5.00). Men consuming fish oil in later life had a lower risk of advanced prostate cancer [HR (95%CI): 0.43 (0.19, 0.95)], no association was found for early life or midlife consumption.
Salted or smoked fish may increase risk of advanced prostate cancer, whereas fish oil consumption may be protective against progression of prostate cancer in elderly men. In a setting with very high fish consumption, no association was found between overall fish consumption in early or midlife and prostate cancer risk.
Lu00FDsingTo access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Files. This article is open access.
RightsArchived with thanks to PloS one
- Rye bread consumption in early life and reduced risk of advanced prostate cancer.
- Authors: Torfadottir JE, Valdimarsdottir UA, Mucci L, Stampfer M, Kasperzyk JL, Fall K, Tryggvadottir L, Aspelund T, Olafsson O, Harris TB, Jonsson E, Tulinius H, Adami HO, Gudnason V, Steingrimsdottir L
- Issue date: 2012 Jun
- Fish and fish-liver oil consumption in adolescence and midlife and risk of CHD in older women.
- Authors: Haraldsdottir A, Torfadottir JE, Valdimarsdottir UA, Aspelund T, Harris TB, Launer LJ, Gudnason V, Steingrimsdottir L
- Issue date: 2016 Feb
- Re: consumption of fish products across the lifespan and prostate cancer risk.
- Authors: Taneja SS
- Issue date: 2014 Jan
- Plasma phospholipid fatty acids and fish-oil consumption in relation to osteoporotic fracture risk in older adults: the Age, Gene/Environment Susceptibility Study.
- Authors: Harris TB, Song X, Reinders I, Lang TF, Garcia ME, Siggeirsdottir K, Sigurdsson S, Gudnason V, Eiriksdottir G, Sigurdsson G, Steingrimsdottir L, Aspelund T, Brouwer IA, Murphy RA
- Issue date: 2015 May
- Early Life Residence, Fish Consumption, and Risk of Breast Cancer.
- Authors: Haraldsdottir A, Steingrimsdottir L, Valdimarsdottir UA, Aspelund T, Tryggvadottir L, Harris TB, Launer LJ, Mucci LA, Giovannucci EL, Adami HO, Gudnason V, Torfadottir JE
- Issue date: 2017 Mar