Type 3 finger length pattern is associated with total knee replacements due to osteoarthritis but not with hip replacements or hand osteoarthritis in the elderly: the AGES-Reykjavik study.
Average rating
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Star rating
Your vote was cast
Thank you for your feedback
Thank you for your feedback
Authors
Sigurjonsdottir, KristinBjorgulfsson, Thorir M
Aspelund, Thor
Eiriksdottir, Gudny
Sigurdsson, Sigurdur
Ingvarsson, Thorvaldur
Harris, Tamara B
Launer, Lenore
Gudnason, Vilmundur
Jonsson, Helgi
Issue Date
2013
Metadata
Show full item recordCitation
BMC Musculoskelet Disord 2013, 14:112Abstract
Recent case-control studies have shown an association between type 3 finger length pattern (longer ring finger than index finger) and knee osteoarthritis. This large cross-sectional study tests the hypothesis that the type 3 pattern is associated with total joint replacements due to osteoarthritis in a large population based study.Finger length ratios were assessed visually on 5170 hand photographs (2975 females, 2195 males, mean age 76). In this population-based multidisciplinary study of aging in Reykjavik, Iceland, the prevalence of osteoarthritis associated total knee replacements was 223(4.3%) and total hip replacements 316(6.1%). We then performed a binary logistic regression analysis for total knee replacements and total hip replacements, including finger length patterns, osteoarthritis at other sites and other variables with possible association to osteoarthritis such as age, BMI and bone mineral density of the spine.
The prevalence of the type 3 pattern was 50% (43% in females, 58% in males). The regression analysis revealed an odds ratio for total knee replacements of 1.65 (1.24-2.2) p = 0.0007, in the type 3 finger pattern group, similar in both genders. This association was independent of the associations we have previously reported between total knee replacements and BMI and the presence of hand osteoarthritis. No association was seen between finger length patterns and total hip replacements.
Finger length patterns read from digital photographs in this large study confirm previous radiographic observations with significant associations between the type 3 pattern and total knee replacements but not total hip replacements in both genders in this elderly group.
Description
To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Files. This article is open access.Additional Links
http://dx.doi.org/10.1186/1471-2474-14-112http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626925/
Rights
openAccessae974a485f413a2113503eed53cd6c53
10.1186/1471-2474-14-112
Scopus Count
Collections
Related articles
- Incidence and prevalence of total joint replacements due to osteoarthritis in the elderly: risk factors and factors associated with late life prevalence in the AGES-Reykjavik Study.
- Authors: Jonsson H, Olafsdottir S, Sigurdardottir S, Aspelund T, Eiriksdottir G, Sigurdsson S, Harris TB, Launer L, Gudnason V
- Issue date: 2016 Jan 12
- The presence of total knee or hip replacements due to osteoarthritis enhances the positive association between hand osteoarthritis and atherosclerosis in women: the AGES-Reykjavik study.
- Authors: Jonsson H, Helgadottir GP, Aspelund T, Eiriksdottir G, Sigurdsson S, Siggeirsdottir K, Ingvarsson T, Harris TB, Launer L, Gudnason V
- Issue date: 2011 Jun
- Association between index-to-ring finger length ratio and risk of severe knee and hip osteoarthritis requiring total joint replacement.
- Authors: Hussain SM, Wang Y, Muller DC, Wluka AE, Giles GG, Manning JT, Graves S, Cicuttini FM
- Issue date: 2014 Jul
- Electronic health databases for epidemiological research on joint replacements: considerations when making cross-national comparisons.
- Authors: Oleske DM, Bonafede MM, Jick S, Ji M, Hall JA
- Issue date: 2014 Sep
- Incidence of total hip or knee replacement due to osteoarthritis in relation to thyroid function: a prospective cohort study (The Nord-Trøndelag Health Study).
- Authors: Hellevik AI, Johnsen MB, Langhammer A, Fenstad AM, Furnes O, Storheim K, Zwart JA, Flugsrud G, Nordsletten L
- Issue date: 2017 May 18