Inflammatory bowel disease in Icelandic children 1951-2010. Population-based study involving one nation over six decades.
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Your vote was cast
Thank you for your feedback
Thank you for your feedback
MetadataShow full item record
CitationScand. J. Gastroenterol. 2013, 48 (12):1399-404
AbstractAIM AND BACKGROUND. We describe the changes in incidence and disease location of inflammatory bowel disease (IBD) in children in one country over six decades. Iceland is an island with centralized health information. Children with IBD are cared for in only two hospitals. Iceland is therefore well suited for nationwide epidemiologic studies. MATERIAL AND METHODS. All IBD patients 16 years and younger diagnosed in Iceland from 1950-2010 were included. Patients were identified retrospectively from 1950-1989, and prospectively from 1990-2010, by reviewing pathology and charts for all patients diagnosed with IBD. Criteria for the diagnosis of ulcerative colitis (UC) were history of blood in stools for >3 weeks, characteristic endoscopic appearance of continuous inflammation of the colon, and histologic appearance of acute and chronic inflammation of the colon without granulomata. Criteria of Crohn's disease (CD) were history of abdominal pain, blood in stools, and endoscopic, radiologic, and histologic features of CD. RESULTS. One hundred and ten children were diagnosed with IBD, 61 with UC, 44 with CD, and 5 with indeterminate disease. The median age was 13.7 ± 2.6, with sex distribution varying from decade to decade. From 1980 until 2000, there was a dramatic increase in the incidence of IBD from 1.2 per 100,000 children <16 years of age to 5.6 per 100,000. However, in the past decade, the incidence has plateaued. CONCLUSION. In this population-based pediatric study, we report an increase in the incidence of IBD from 1950-2000. Incidence in Icelandic children is lower than in published studies from other Northern European countries.
DescriptionTo access publisher's full text version of this article click on the hyperlink at the bottom of the page
RightsArchived with thanks to Scandinavian journal of gastroenterology
- Increasing incidences of inflammatory bowel disease and decreasing surgery rates in Copenhagen City and County, 2003-2005: a population-based study from the Danish Crohn colitis database.
- Authors: Vind I, Riis L, Jess T, Knudsen E, Pedersen N, Elkjaer M, Bak Andersen I, Wewer V, Nørregaard P, Moesgaard F, Bendtsen F, Munkholm P, DCCD study group.
- Issue date: 2006 Jun
- [Pediatric inflammatory bowel disease: is it still increasing?].
- Authors: Fernandes A, Bacalhau S, Cabral J
- Issue date: 2011 Dec
- Incidence of inflammatory bowel disease in Iceland 1995 - 2009. A nationwide population-based study.
- Authors: Björnsson S, Tryggvason FÞ, Jónasson JG, Cariglia N, Örvar K, Kristjánsdóttir S, Stefansson T
- Issue date: 2015
- Inflammatory bowel disease in Iceland, 1990-1994: a prospective, nationwide, epidemiological study.
- Authors: Björnsson S, Jóhannsson JH
- Issue date: 2000 Jan
- The incidence of inflammatory bowel disease in a rural region of Southern Germany: a prospective population-based study.
- Authors: Ott C, Obermeier F, Thieler S, Kemptner D, Bauer A, Schölmerich J, Rogler G, Timmer A
- Issue date: 2008 Sep