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dc.contributor.authorOlafsdottir, Eydis
dc.contributor.authorAndersson, Dan K G
dc.contributor.authorDedorsson, Inger
dc.contributor.authorStefánsson, Einar
dc.date.accessioned2014-08-29T14:08:16Z
dc.date.available2014-08-29T14:08:16Z
dc.date.issued2014-03
dc.identifier.citationActa Ophthalmol. 2014, 92 (2):133-7en
dc.identifier.issn1755-3768
dc.identifier.pmid23452444
dc.identifier.doi10.1111/aos.12095
dc.identifier.urihttp://hdl.handle.net/2336/325567
dc.descriptionTo access publisher's full text version of this article click on the hyperlink at the bottom of the pageen
dc.description.abstractTo evaluate the prevalence of and risk factors for, retinopathy in a geographically defined population with type 2 diabetes mellitus compared with a control group of subjects without diabetes, matched by age, sex and residence in order to find the retinopathy attributable to type 2 diabetes.
dc.description.abstractThe study populations are, on one hand, a prevalence cohort of subjects with type 2 diabetes resident in the community of Laxå, Sweden, and on the other a control group, matched by age, gender and residence with those with a diagnosis of type 2 diabetes mellitus. Retinopathy was graded from fundus photographs using a modification of the Early Treatment Retinopathy Study (ETDRS) adaptation of the modified Airlie House classification of diabetic retinopathy (DR).
dc.description.abstractAny retinopathy was found in 34.6% in the type 2 diabetes cohort and in 8.8% in the control group without diabetes. Among the diabetic patients, any retinopathy was significantly associated with duration of diabetes (p = 0.0001), HbA1c (p = 0.0056), systolic blood pressure (p = 0.0091) and lower serum cholesterol (p = 0.0197) in multivariate logistic regression analyses. Having retinopathy in the control group was associated only with systolic blood pressure (p = 0.0014) in logistic regression analysis.
dc.description.abstractThe prevalence of retinopathy among patients with type 2 diabetes in Laxå, Sweden, was similar or somewhat lower compared with other studies in the Nordic countries. The prevalence of retinopathy in a control group without diabetes equalled numbers from population studies worldwide. Our study indicates that the retinopathy that can be attributed to hyperglycaemia in the diabetic state is less common than is usually accounted for. A considerable fraction of retinopathy in subjects with diabetes may instead be due to other factors such as hypertension and should thus be treated correspondingly.
dc.description.sponsorshipOrebro County Council, Orebro, Sweden Research foundation of the National University Hospital, Reykjavik, Iceland Helga Jonsdottir and Sigurlidi Kristjansson Memorial Fund, Reykjavik, Icelanden
dc.language.isoenen
dc.publisherWiley-Blackwellen
dc.relation.urlhttp://dx.doi.org/10.1111/aos.12095en
dc.relation.urlhttp://onlinelibrary.wiley.com/doi/10.1111/aos.12095/pdfen
dc.rightsArchived with thanks to Acta ophthalmologicaen
dc.subjectSykursýkien
dc.subjectBlóðþrýstinguren
dc.subjectBlóðfitaen
dc.subjectSjónskerðingen
dc.subjectBlóðsykuren
dc.subject.meshAgeden
dc.subject.meshBlood Glucoseen
dc.subject.meshBlood Pressureen
dc.subject.meshCholesterolen
dc.subject.meshDiabetes Mellitus, Type 2en
dc.subject.meshDiabetic Retinopathyen
dc.subject.meshFemaleen
dc.subject.meshHemoglobin A, Glycosylateden
dc.subject.meshHumansen
dc.subject.meshMaleen
dc.subject.meshMiddle Ageden
dc.subject.meshPrevalenceen
dc.subject.meshRisk Factorsen
dc.subject.meshSwedenen
dc.subject.meshVisual Acuityen
dc.titleThe prevalence of retinopathy in subjects with and without type 2 diabetes mellitus.en
dc.typeArticleen
dc.contributor.departmentNatl Univ Hosp Reykjavik, Dept Ophthalmol, Reykjavik, Iceland, Univ Iceland, Reykjavik, Iceland, Orebro Univ Hosp, Dept Ophthalmol, S-70185 Orebro, Sweden, Uppsala Univ, Dept Publ Hlth & Caring Sci, Family Med & Clin Epidemiol Sect, Uppsala, Swedenen
dc.identifier.journalActa ophthalmologicaen
dc.rights.accessLandspitali Access - LSH-aðganguren
html.description.abstractTo evaluate the prevalence of and risk factors for, retinopathy in a geographically defined population with type 2 diabetes mellitus compared with a control group of subjects without diabetes, matched by age, sex and residence in order to find the retinopathy attributable to type 2 diabetes.
html.description.abstractThe study populations are, on one hand, a prevalence cohort of subjects with type 2 diabetes resident in the community of Laxå, Sweden, and on the other a control group, matched by age, gender and residence with those with a diagnosis of type 2 diabetes mellitus. Retinopathy was graded from fundus photographs using a modification of the Early Treatment Retinopathy Study (ETDRS) adaptation of the modified Airlie House classification of diabetic retinopathy (DR).
html.description.abstractAny retinopathy was found in 34.6% in the type 2 diabetes cohort and in 8.8% in the control group without diabetes. Among the diabetic patients, any retinopathy was significantly associated with duration of diabetes (p = 0.0001), HbA1c (p = 0.0056), systolic blood pressure (p = 0.0091) and lower serum cholesterol (p = 0.0197) in multivariate logistic regression analyses. Having retinopathy in the control group was associated only with systolic blood pressure (p = 0.0014) in logistic regression analysis.
html.description.abstractThe prevalence of retinopathy among patients with type 2 diabetes in Laxå, Sweden, was similar or somewhat lower compared with other studies in the Nordic countries. The prevalence of retinopathy in a control group without diabetes equalled numbers from population studies worldwide. Our study indicates that the retinopathy that can be attributed to hyperglycaemia in the diabetic state is less common than is usually accounted for. A considerable fraction of retinopathy in subjects with diabetes may instead be due to other factors such as hypertension and should thus be treated correspondingly.


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