Öndunar- og meltingarfæraeinkenni hjá 7-10 ára börnum í Reykjavík
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Issue Date
2015-03
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Respiratory and gastrointestinal symptoms in 7-10 year old children in Reykjavík, Iceland.Citation
Læknablaðið 101 (3):131-135Abstract
Inngangur: Astmi og nefbólgur eru algengir sjúkdómar sem orsakast oft af ofnæmi, en verða þó ekki nærri alltaf skýrðir með því. Vélindabakflæði er einnig algengt vandamál sem er stundum talið valda bæði bólgum í nefi og astma. Tilgangur rannsóknarinnar var að kanna hvert væri samband einkenna um vélindabakflæði og öndunarfæraeinkenna hjá 7-10 ára börnum í Reykjavík. Efniviður og aðferðir: Árin 2008-2009 voru sendir út 2895 stuttir spurningalistar til 7-10 ára barna í grunnskólum Reykjavíkur til þess að skima fyrir fæðuofnæmi, sem hluti af fjölþjóðarannsókn á fæðuofnæmi. Svör bárust fyrir 2346 börn (81%). Úr þeim hópi voru 176 börn (7,5%) valin sem svöruðu spurningu um óþægindi af mat játandi og 317 börn sem svöruðu spurningunni neitandi. Þessir hópar svöruðu ítarlegum spurningalista, meðal annars um einkenni frá nefi, berkjum og um bakflæði. Borin var saman fylgni einkenna frá nefi og berkjum annars vegar og bakflæði hins vegar. Niðurstöður: Sterk fylgni var milli surgs í brjósti á síðasta ári og uppkasta (p<0,001), ógleði (p<0,001) og brjóstsviða (p<0,001) á síðustu 6 mánuðum. Einnig var fylgni milli astma og ógleði (p<0,05), og astma og brjóstsviða (p<0,001) og milli nefeinkenna annars vegar og uppkasta (p<0,01), ógleði (p<0,01), brjóstsviða (p<0,01) og súrs bragðs í munni (p<0,001) hins vegar. Ályktun: Rannsóknin sýnir sterkt samband milli bakflæðiseinkenna annars vegar og nefeinkenna, surgs og astma hins vegar þó að enn sé óljóst hvers eðlis þetta samband er. Hafa ber bakflæðissjúkdóm í huga ef astmi og nefeinkenni skýrast ekki af öðrum ástæðum.Introduction: Asthma and rhinitis are common diseases in children often but not always caused by allergy. Gastroesophageal reflux is also prevalent in children and relationship with respiratory symptoms has been suggested. The aim of this study was to investigate this relationship in schoolchildren. Material and methods: As a part of multi-centre cross-sectional food allergy study (Europrevall), a short questionnaire was sent out to 2895 schoolchildren in Reykjavik 7-10 year old. Of the 2346 (81%) children we received answers from we selected those that answered positively to questions regarding common foods and a random sample of those who denied any symptoms related to food. The selected children were invited to further study where they answered an extensive questionnaire that included questions regarding respiratory and gastrointestinal symptoms. Results: A significant correlation was found between a history of wheezing over the previous year and vomiting, (p<0.001) and feeling nauseous (p<0.001) in the past 6 months. There was also a correlation between asthma in the previous year and feeling nauseous (p<0.05), having a a burning or painful feeling in the middle of the chest (p<0.001) as well as nasal symptoms and vomiting (p<0.01), feeling nauseous (p<0.01), having a burning or painful feeling in the middle of the chest (p<0.01) and having a sour taste, like a taste of vomit in the mouth (p<0.001). Conclusion: This study shows a significant correlation between symptoms of gastroesophageal reflux and respiratory and nasal symptoms. Clinicians should be aware of this association though the nature and direction of this association is still unclear.
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