Linking exposure to polychlorinated biphenyls with fatty fish consumption and reduced fetal growth among Danish pregnant women: a cause for concern?
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Your vote was cast
Thank you for your feedback
Thank you for your feedback
MetadataShow full item record
CitationAm. J. Epidemiol. 2008, 168(8):958-65
AbstractIn a selected group of women from the Danish National Birth Cohort, the authors investigated the association between intake of fatty fish and plasma concentrations of polychlorinated biphenyls (PCBs) on the one hand and the association between maternal PCB concentrations and fetal growth on the other. Of 70,183 women who filled in a food frequency questionnaire during 1996-2002, 100 nulliparous women aged 25-35 years with normal prepregnancy body mass index were selected according to their intake of fatty fish (low (0 meals/month, n = 34), medium (1-3 meals/month, n = 33), or high (> or = meals/month, n = 33)). Women with a high intake of fatty fish had 50% (95% confidence interval (CI): 31, 72) higher plasma PCB concentrations than women with low intake. Maternal plasma PCB concentrations were inversely associated with birth weight and placental weight. The adjusted mean difference between the 75th and 25th PCB percentiles was -155 g (95% CI: -291, -19) for birth weight and -81 g (95% CI: -135, -26) for placental weight. These results support previous findings from this cohort, where fatty fish intake was inversely associated with fetal growth. Dietary recommendations often encourage weekly consumption of fatty fish. These results suggest that potential exposure to PCBs should be carefully considered before recommending such intakes among women of childbearing age.
DescriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links field
- Is high consumption of fatty fish during pregnancy a risk factor for fetal growth retardation? A study of 44,824 Danish pregnant women.
- Authors: Halldorsson TI, Meltzer HM, Thorsdottir I, Knudsen V, Olsen SF
- Issue date: 2007 Sep 15
- Associations between marine food consumption and plasma concentrations of POPs in a Norwegian coastal population.
- Authors: Rylander C, Sandanger TM, Brustad M
- Issue date: 2009 Feb
- Maternal concentration of polychlorinated biphenyls and dichlorodiphenyl dichlorethylene and birth weight in Michigan fish eaters: a cohort study.
- Authors: Karmaus W, Zhu X
- Issue date: 2004 Jan 28
- Polychlorinated biphenyls in blood plasma among Swedish female fish consumers in relation to low birth weight.
- Authors: Rylander L, Strömberg U, Dyremark E, Ostman C, Nilsson-Ehle P, Hagmar L
- Issue date: 1998 Mar 1
- Fish consumption and other environmental exposures and their associations with serum PCB concentrations among Mohawk women at Akwesasne.
- Authors: Fitzgerald EF, Hwang SA, Langguth K, Cayo M, Yang BZ, Bush B, Worswick P, Lauzon T
- Issue date: 2004 Feb