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dc.contributor.authorBjarnadottir, Gudrun D
dc.contributor.authorHaraldsson, Haraldur M
dc.contributor.authorRafnar, Bjarni O
dc.contributor.authorSigurdsson, Engilbert
dc.contributor.authorSteingrimsson, Steinn
dc.contributor.authorJohannsson, Magnus
dc.contributor.authorBragadottir, Helena
dc.contributor.authorMagnusson, Andres
dc.date.accessioned2015-06-11T10:29:47Zen
dc.date.available2015-06-11T10:29:47Zen
dc.date.issued2015en
dc.date.submitted2015en
dc.identifier.citationJ Addict Med. 2015, 9 (3):188-94en
dc.identifier.issn1935-3227en
dc.identifier.pmid25748561en
dc.identifier.doi10.1097/ADM.0000000000000115en
dc.identifier.urihttp://hdl.handle.net/2336/556709en
dc.description.abstractPrescription rates of methylphenidate (MPH) are sharply rising in most Western countries. Although it has been reported that MPH has abuse potential, little is known about the prevalence of intravenous (IV) abuse of MPH. The aim of the study was to investigate the prevalence of IV MPH abuse among treatment-seeking IV substance abusers in Iceland.
dc.description.abstractThis is a descriptive population-based study using a semistructured interview assessing sociodemographics, substance abuse history, and the method of administration of 108 IV substance abusers. During 1 year, consecutively admitted adult inpatients with substance use disorder at any detoxification center in Iceland that reported any IV substance abuse in the past 30 days were invited to participate. Abuse was defined as nontherapeutic use of a substance to gain psychological or physiological effect.
dc.description.abstractPrevalence of any IV MPH abuse among participants was 88% in the last 30 days (95% confidence interval [CI], 0.82-0.94) and MPH was the most commonly abused substance (65%) and the preferred substance (63%). Around one third (30%) reported MPH as the first IV substance ever abused. However, among those reporting a shorter history than 10 years of IV abuse, 42% reported MPH as the first IV substance ever abused.
dc.description.abstractThis first nationwide study on IV abuse of MPH shows that it is common among treatment-seeking IV abusers in Iceland and suggests that MPH has high abuse potential. Therefore, both the use and possible abuse of MPH in those with high abuse potential should be monitored, especially in countries where MPH prescriptions rates are on the rise.
dc.language.isoenen
dc.publisherWolters Kluwer Health | Lippincott Williams & Wilkinsen
dc.relation.urlhttp://dx.doi.org/ 10.1097/ADM.0000000000000115en
dc.rightsArchived with thanks to Journal of addiction medicineen
dc.subjectLyfjamisnotkunen
dc.subject.meshMethylphenidateen
dc.subject.meshSubstance Abuse, Intravenousen
dc.subject.meshSorption Detoxificationen
dc.subject.meshPrescription Drug Misuseen
dc.subject.meshCentral Nervous System Stimulantsen
dc.titlePrevalent intravenous abuse of methylphenidate among treatment-seeking patients with substance abuse disorders: a descriptive population-based study.en
dc.typeArticleen
dc.contributor.departmentMental Health Services, Landspitali-the National University Hospital (GDB, HMH, BOR, ES, HB), Reykjavik, Iceland; Centre for Ethics, Law and Mental Health (SS), Institute of Neuroscience and Physiology, The Sahlgrenska Academy, The University of Gothenburg, Gothenburg, Sweden; School of Health Sciences (GDB, HMH, BOR, ES, AM), Faculty of Medicine, University of Iceland, Reykjavík, Iceland; and Department of Pharmacology and Toxicology (MJ), Faculty of Medicine, University of Iceland, Reykjavik, Iceland.en
dc.identifier.journalJournal of addiction medicineen
dc.rights.accessOpen Accessen
refterms.dateFOA2018-09-12T15:15:48Z
html.description.abstractPrescription rates of methylphenidate (MPH) are sharply rising in most Western countries. Although it has been reported that MPH has abuse potential, little is known about the prevalence of intravenous (IV) abuse of MPH. The aim of the study was to investigate the prevalence of IV MPH abuse among treatment-seeking IV substance abusers in Iceland.
html.description.abstractThis is a descriptive population-based study using a semistructured interview assessing sociodemographics, substance abuse history, and the method of administration of 108 IV substance abusers. During 1 year, consecutively admitted adult inpatients with substance use disorder at any detoxification center in Iceland that reported any IV substance abuse in the past 30 days were invited to participate. Abuse was defined as nontherapeutic use of a substance to gain psychological or physiological effect.
html.description.abstractPrevalence of any IV MPH abuse among participants was 88% in the last 30 days (95% confidence interval [CI], 0.82-0.94) and MPH was the most commonly abused substance (65%) and the preferred substance (63%). Around one third (30%) reported MPH as the first IV substance ever abused. However, among those reporting a shorter history than 10 years of IV abuse, 42% reported MPH as the first IV substance ever abused.
html.description.abstractThis first nationwide study on IV abuse of MPH shows that it is common among treatment-seeking IV abusers in Iceland and suggests that MPH has high abuse potential. Therefore, both the use and possible abuse of MPH in those with high abuse potential should be monitored, especially in countries where MPH prescriptions rates are on the rise.


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