Dietary protein-to-carbohydrate ratio and added sugar as determinants of excessive gestational weight gain: a prospective cohort study.
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Your vote was cast
Thank you for your feedback
Thank you for your feedback
MetadataShow full item record
CitationBMJ Open 2015, 5 (2):e005839
AbstractTo examine the relation between the protein:carbohydrate (P/C) ratio and added sugar intake in pregnancy and gestational weight gain (GWG).
A prebirth cohort including 103 119 pregnancies enrolled between 1996 and 2003.
All women in Denmark were eligible to participate if they spoke Danish and were planning to carry to term.The pregnant women were recruited and enrolled during their first antenatal visit (6-10 weeks of gestation).
Participants included women with live-born singletons and complete data on dietary intake and GWG, leaving 46 262 women for the analysis.
Macronutrient intake was quantified using a validated food frequency questionnaire administered in the 25th week of gestation. The P/C ratio and added sugar intake were examined in quintiles.
GWG was based on self-reported weight in gestational weeks 12 and 30 and defined as gain in g/week. We used multivariable linear regression, including adjusting for pre-pregnancy body mass index, to calculate relative change in GWG and 95% CI.
Average GWG was 471(224) g/week. The adjusted weight gain was 16 g/week lower (95% CI 9 to 22, p for trend <0.001) in the highest (Q5) versus lowest (Q1) quintile of the P/C ratio (∼3% average reduction across the entire pregnancy). Weight gain for those with >20%E vs <12%E from protein was 36 g/week lower (95% CI 20 to 53, p for trend <0.0001; ∼8% average reduction). A high P/C ratio was inversely related to intake of added sugars. Added sugar consumption was strongly associated with GWG (Q5 vs Q1: 34, 95% CI 28 to 40 g/week, p for trend <0.0001).
A high P/C ratio was associated with reduced GWG. This association appeared to be partly driven by a decrease in intake of added sugar. These results are consistent with randomised trials in non-pregnant participants. A dietary intervention targeting an increased P/C ratio with emphasis on reducing added sugar can contribute to reducing excessive GWG.
DescriptionTo access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Files. This article is open access.
RightsArchived with thanks to BMJ open
- Maternal diet but not gestational weight gain predicts central adiposity accretion in utero among pregnant adolescents.
- Authors: Whisner CM, Young BE, Pressman EK, Queenan RA, Cooper EM, O'Brien KO
- Issue date: 2015 Apr
- [Energy intake as determinants of gestational weight gain in Chengdu].
- Authors: Yang L, Wu C, Bao Y, Zhou F, Lan X, Zhang Y, Zhao R, Zhang J, Zeng G
- Issue date: 2018 Nov
- A Priori and a Posteriori Dietary Patterns during Pregnancy and Gestational Weight Gain: The Generation R Study.
- Authors: Tielemans MJ, Erler NS, Leermakers ET, van den Broek M, Jaddoe VW, Steegers EA, Kiefte-de Jong JC, Franco OH
- Issue date: 2015 Nov 12
- Intake of Sweets, Snacks and Soft Drinks Predicts Weight Gain in Obese Pregnant Women: Detailed Analysis of the Results of a Randomised Controlled Trial.
- Authors: Renault KM, Carlsen EM, Nørgaard K, Nilas L, Pryds O, Secher NJ, Olsen SF, Halldorsson TI
- Issue date: 2015
- Effects of lifestyle intervention on dietary intake, physical activity level, and gestational weight gain in pregnant women with different pre-pregnancy Body Mass Index in a randomized control trial.
- Authors: Hui AL, Back L, Ludwig S, Gardiner P, Sevenhuysen G, Dean HJ, Sellers E, McGavock J, Morris M, Jiang D, Shen GX
- Issue date: 2014 Sep 24