Do patients initiate therapy? Primary non-adherence to statins and antidepressants in Iceland.
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Your vote was cast
Thank you for your feedback
Thank you for your feedback
MetadataShow full item record
CitationInt. J. Clin. Pract. 2015, 69 (5):597-603
AbstractPrimary non-adherence occurs when a drug has been prescribed but the patient fails to have it dispensed at the pharmacy.
To assess primary non-adherence to statins and antidepressants in Iceland, the association of demographic factors with primary non-adherence, and the time from when a prescription is issued until it is dispensed.
Data on patients receiving a new prescription for a statin or an antidepressant from the Primary Health Care database were linked with dispensing histories from The Icelandic Prescription Database. The proportion of patients who did not have their prescription dispensed within a year from issuing (primary non-adherent) was assessed, as well as the time from issue until dispensing. Associations between demographic factors and primary non-adherence were estimated using logistic regression.
The overall primary non-adherence was 6.3% and 8.0% for statins and antidepressants, respectively. The majority of patients had their prescription dispensed within 7 days (85% for statins, 87% for antidepressants). Being disabled and receiving a prescription for an expensive drug was associated with higher rates of primary non-adherence.
The rate of primary non-adherence to statins and antidepressants in Iceland is low. Vulnerable groups such as the disabled should be given special attention when new drugs are prescribed.
DescriptionTo access publisher's full text version of this article click on the hyperlink at the bottom of the page
RightsArchived with thanks to International journal of clinical practice
- Higher costs and therapeutic factors associated with adherence to NCQA HEDIS antidepressant medication management measures: analysis of administrative claims.
- Authors: Robinson RL, Long SR, Chang S, Able S, Baser O, Obenchain RL, Swindle RW
- Issue date: 2006 Jan-Feb
- Analysis of factors associated with statin adherence in a hierarchical model considering physician, pharmacy, patient, and prescription characteristics.
- Authors: Pedan A, Varasteh L, Schneeweiss S
- Issue date: 2007 Jul-Aug
- Association of copayment with likelihood and level of adherence in new users of statins: a retrospective cohort study.
- Authors: Watanabe JH, Kazerooni R, Bounthavong M
- Issue date: 2014 Jan
- Impact of prescription size on statin adherence and cholesterol levels.
- Authors: Batal HA, Krantz MJ, Dale RA, Mehler PS, Steiner JF
- Issue date: 2007 Oct 25
- Using primary care prescribing data to improve GP awareness of antidepressant adherence issues.
- Authors: Mabotuwana T, Warren J, Orr M, Kenealy T, Harrison J
- Issue date: 2011