Severe, very early onset pre-eclampsia associated with liquorice consumption.

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Authors
Hauksdottir, Dögg
Sigurjonsdottir, Helga Agusta
Arnadottir, Margret
Geirsson, Reynir T
Issue Date
2015-05

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Citation
Hypertens Pregnancy 2015, 34 (2):221-6
Abstract
We present the case of very early onset pre-eclampsia, possibly aggravated by liquorice consumption.
An 18-year-old healthy primigravida presented with high blood pressure and proteinuria at 18 weeks gestation. She had a strong family history of pre-eclampsia and was consuming considerable amounts of liquorice. A diagnosis of severe pre-eclampsia/hemolysis, elevated liver enzymes, and low platelet count was confirmed. The pregnancy was terminated. Extensive investigation ruled out underlying diseases and autopsy revealed a normal fetus. In three consequtive pregnancies, she developed milder forms of pre-eclampsia.
In healthy women with a familial/genetic susceptibility for pre-eclampsia, liquorice consumption may aggravate the course of the disease.
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