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dc.contributor.authorHalldorsson, Bjarni V
dc.contributor.authorBjornsson, Aron Hjalti
dc.contributor.authorGudmundsson, Haukur Tyr
dc.contributor.authorBirgisson, Elvar Orn
dc.contributor.authorLudviksson, Bjorn Runar
dc.contributor.authorGudbjornsson, Bjorn
dc.date.accessioned2015-09-11T11:54:05Zen
dc.date.available2015-09-11T11:54:05Zen
dc.date.issued2015en
dc.date.submitted2015en
dc.identifier.citationComput Math Methods Med. 2015, 2015:189769en
dc.identifier.issn1748-6718en
dc.identifier.pmid25815042en
dc.identifier.doi10.1155/2015/189769en
dc.identifier.urihttp://hdl.handle.net/2336/577177en
dc.descriptionTo access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Files. This article is open access.en
dc.description.abstractExpanding medical knowledge increases the potential risk of medical errors in clinical practice. We present, OPAD, a clinical decision support system in the field of the medical care of osteoporosis. We utilize clinical information from international guidelines and experts in the field of osteoporosis. Physicians are provided with user interface to insert standard patient data, from which OPAD provides instant diagnostic comments, 10-year risk of fragility fracture, treatment options for the given case, and when to offer a follow-up DXA-evaluation. Thus, the medical decision making is standardized according to the best expert knowledge at any given time. OPAD was evaluated in a set of 308 randomly selected individuals. OPAD's ten-year fracture risk computation is nearly identical to FRAX (r = 0.988). In 58% of cases OPAD recommended DXA evaluation at the present time. Following a DXA measurement in all individuals, 71% of those that were recommended to have DXA at the present time received recommendation for further investigation or specific treatment by the OPAD. In only 5.9% of individuals in which DXA was not recommended, the result of the BMD measurement changed the recommendations given by OPAD.
dc.language.isoenen
dc.publisherHindawi Publishing Corporationen
dc.relation.urlhttp://dx.doi.org/ 10.1155/2015/189769en
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359799/en
dc.rightsArchived with thanks to Computational and mathematical methods in medicineen
dc.subjectBeinþynningen
dc.subjectMjaðmarbroten
dc.subject.meshHip Fracturesen
dc.subject.meshWomenen
dc.subject.meshBone Densityen
dc.subject.meshMenen
dc.subject.meshOsteoporosisen
dc.subject.meshDecision Support Systems, Clinicalen
dc.titleA clinical decision support system for the diagnosis, fracture risks and treatment of osteoporosis.en
dc.typeArticleen
dc.contributor.department[ 1 ] Reykjavik Univ, Sch Sci & Engn, Inst Biomed & Neural Engn, IS-101 Reykjavik, Iceland [ 2 ] Univ Hosp, Ctr Rheumatol Res, IS-101 Reykjavik, Iceland [ 3 ] Univ Debrecen, Fac Med, H-4032 Debrecen, Hungary [ 4 ] Univ Iceland, Fac Med, IS-101 Reykjavik, Iceland [ 5 ] Akureyri Hosp, Osteoporosis Clin, IS-600 Akureyri, Iceland [ 6 ] Univ Hosp, Dept Immunol, IS-101 Reykjavik, Icelanden
dc.identifier.journalComputational and mathematical methods in medicineen
dc.rights.accessOpen Accessen
refterms.dateFOA2018-09-12T15:34:32Z
html.description.abstractExpanding medical knowledge increases the potential risk of medical errors in clinical practice. We present, OPAD, a clinical decision support system in the field of the medical care of osteoporosis. We utilize clinical information from international guidelines and experts in the field of osteoporosis. Physicians are provided with user interface to insert standard patient data, from which OPAD provides instant diagnostic comments, 10-year risk of fragility fracture, treatment options for the given case, and when to offer a follow-up DXA-evaluation. Thus, the medical decision making is standardized according to the best expert knowledge at any given time. OPAD was evaluated in a set of 308 randomly selected individuals. OPAD's ten-year fracture risk computation is nearly identical to FRAX (r = 0.988). In 58% of cases OPAD recommended DXA evaluation at the present time. Following a DXA measurement in all individuals, 71% of those that were recommended to have DXA at the present time received recommendation for further investigation or specific treatment by the OPAD. In only 5.9% of individuals in which DXA was not recommended, the result of the BMD measurement changed the recommendations given by OPAD.


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