Trends in dialysis modality choice and related patient survival in the ERA-EDTA Registry over a 20-year period.
dc.contributor.author | van de Luijtgaarden, Moniek W M | |
dc.contributor.author | Jager, Kitty J | |
dc.contributor.author | Segelmark, Mårten | |
dc.contributor.author | Pascual, Julio | |
dc.contributor.author | Collart, Frederic | |
dc.contributor.author | Hemke, Aline C | |
dc.contributor.author | Remón, César | |
dc.contributor.author | Metcalfe, Wendy | |
dc.contributor.author | Miguel, Alfonso | |
dc.contributor.author | Kramar, Reinhard | |
dc.contributor.author | Aasarød, Knut | |
dc.contributor.author | Abu Hanna, Ameen | |
dc.contributor.author | Krediet, Raymond T | |
dc.contributor.author | Schön, Staffan | |
dc.contributor.author | Ravani, Pietro | |
dc.contributor.author | Caskey, Fergus J | |
dc.contributor.author | Couchoud, Cecile | |
dc.contributor.author | Palsson, Runolfur | |
dc.contributor.author | Wanner, Christoph | |
dc.contributor.author | Finne, Patrik | |
dc.contributor.author | Noordzij, Marlies | |
dc.date.accessioned | 2016-04-19T11:14:31Z | en |
dc.date.available | 2016-04-19T11:14:31Z | en |
dc.date.issued | 2016-01 | en |
dc.date.submitted | 2016 | en |
dc.identifier.citation | Nephrol. Dial. Transplant. 2016, 31 (1):120-8 | en |
dc.identifier.issn | 1460-2385 | en |
dc.identifier.pmid | 26311215 | en |
dc.identifier.doi | 10.1093/ndt/gfv295 | en |
dc.identifier.uri | http://hdl.handle.net/2336/605875 | en |
dc.description | To access publisher's full text version of this article click on the hyperlink at the bottom of the page | en |
dc.description.abstract | Although previous studies suggest similar patient survival for peritoneal dialysis (PD) and haemodialysis (HD), PD use has decreased worldwide. We aimed to study trends in the choice of first dialysis modality and relate these to variation in patient and technique survival and kidney transplant rates in Europe over the last 20 years. | |
dc.description.abstract | We used data from 196 076 patients within the European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry who started renal replacement therapy (RRT) between 1993 and 2012. Trends in the incidence rate and prevalence on Day 91 after commencing RRT were quantified with Joinpoint regression. Crude and adjusted hazard ratios (HRs) for 5-year dialysis patient and technique survival were calculated using Cox regression. Analyses were repeated using propensity score matching to control for confounding by indication. | |
dc.description.abstract | PD prevalence dropped since 2007 and HD prevalence stabilized since 2009. Incidence rates of PD and HD decreased from 2000 and 2009, respectively, while the incidence of kidney transplantation increased from 1993 onwards. Similar 5-year patient survival for PD versus HD patients was found in 1993-97 [adjusted HR: 1.02, 95% confidence interval (95% CI): 0.98-1.06], while survival was higher for PD patients in 2003-07 (HR: 0.91, 95% CI: 0.88-0.95). Both PD (HR: 0.95, 95% CI: 0.91-1.00) and HD technique survival (HR: 0.93, 95% CI: 0.87-0.99) improved in 2003-07 compared with 1993-97. | |
dc.description.abstract | Although initiating RRT on PD was associated with favourable patient survival when compared with starting on HD treatment, PD was often not selected as initial dialysis modality. Over time, we observed a significant decline in PD use and a stabilization in HD use. These observations were explained by the lower incidence rate of PD and HD and the increase in pre-emptive transplantation. | |
dc.language.iso | en | en |
dc.publisher | Oxford Univ Press | en |
dc.relation.url | http://dx.doi.org/ 10.1093/ndt/gfv295 | en |
dc.rights | Archived with thanks to Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association | en |
dc.subject | Nýrnabilun | en |
dc.subject | Blóðskilun | en |
dc.subject | NEP12 | |
dc.subject.mesh | Kidney Failure, Chronic | en |
dc.subject.mesh | Renal Dialysis | en |
dc.subject.mesh | Peritoneal Dialysis | en |
dc.subject.mesh | Survival Analysis | en |
dc.title | Trends in dialysis modality choice and related patient survival in the ERA-EDTA Registry over a 20-year period. | en |
dc.type | Article | en |
dc.contributor.department | [ 1 ] Univ Amsterdam, Acad Med Ctr, Dept Med Informat, ERA EDTA Registry, Amsterdam, Netherlands [ 2 ] Linkoping Univ, Dept Nephrol, Linkoping, Sweden [ 3 ] Linkoping Univ, Dept Med & Hlth Sci, Linkoping, Sweden [ 4 ] Hosp del Mar, Dept Nephrol, Barcelona, Spain [ 5 ] French Speaking Belgium ESRD Registry, Brussels, Belgium [ 6 ] Nefrovisie RENINE, Leiden, Netherlands [ 7 ] SICATA Informat Syst Andalusian Transplant Autono, Andalucia, Spain [ 8 ] Scottish Renal Registry, Glasgow, Lanark, Scotland [ 9 ] Univ Clin Hosp, Dept Nephrol, Valencia, Spain [ 10 ] OEDTR, Austrian Dialysis & Transplant Registry, Linz, Austria [ 11 ] St Olavs Hosp HF, Dept Nephrol, Trondheim, Norway [ 12 ] Univ Amsterdam, Acad Med Ctr, Dept Med Informat, Meibergdreef 9, NL-1105 AZ Amsterdam, Netherlands [ 13 ] Univ Amsterdam, Acad Med Ctr, Div Nephrol, Meibergdreef 9, NL-1105 AZ Amsterdam, Netherlands [ 14 ] Diaverum Renal Serv Grp, Lund, Sweden [ 15 ] Univ Calgary, Dept Med & Community Hlth Sci, Calgary, AB, Canada [ 16 ] Southmead Hosp, UK Renal Registry, Bristol BS10 5NB, Avon, England [ 17 ] Biomed Agcy, REIN Registry, St Denis, France [ 18 ] Landspitali Natl Univ Hosp Iceland, Div Nephrol, Reykjavik, Iceland [ 19 ] Univ Iceland, Sch Hlth Sci, Fac Med, Reykjavik, Iceland [ 20 ] Univ Hosp Wurzburg, Div Nephrol, Wurzburg, Germany [ 21 ] Finnish Registry Kidney Dis, Helsinki, Finland | en |
dc.identifier.journal | Nephrol Dial Transplant. | en |
dc.rights.access | National Consortium - Landsaðgangur | en |
html.description.abstract | Although previous studies suggest similar patient survival for peritoneal dialysis (PD) and haemodialysis (HD), PD use has decreased worldwide. We aimed to study trends in the choice of first dialysis modality and relate these to variation in patient and technique survival and kidney transplant rates in Europe over the last 20 years. | |
html.description.abstract | We used data from 196 076 patients within the European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry who started renal replacement therapy (RRT) between 1993 and 2012. Trends in the incidence rate and prevalence on Day 91 after commencing RRT were quantified with Joinpoint regression. Crude and adjusted hazard ratios (HRs) for 5-year dialysis patient and technique survival were calculated using Cox regression. Analyses were repeated using propensity score matching to control for confounding by indication. | |
html.description.abstract | PD prevalence dropped since 2007 and HD prevalence stabilized since 2009. Incidence rates of PD and HD decreased from 2000 and 2009, respectively, while the incidence of kidney transplantation increased from 1993 onwards. Similar 5-year patient survival for PD versus HD patients was found in 1993-97 [adjusted HR: 1.02, 95% confidence interval (95% CI): 0.98-1.06], while survival was higher for PD patients in 2003-07 (HR: 0.91, 95% CI: 0.88-0.95). Both PD (HR: 0.95, 95% CI: 0.91-1.00) and HD technique survival (HR: 0.93, 95% CI: 0.87-0.99) improved in 2003-07 compared with 1993-97. | |
html.description.abstract | Although initiating RRT on PD was associated with favourable patient survival when compared with starting on HD treatment, PD was often not selected as initial dialysis modality. Over time, we observed a significant decline in PD use and a stabilization in HD use. These observations were explained by the lower incidence rate of PD and HD and the increase in pre-emptive transplantation. |