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Preferences for prenatal tests for Down syndrome: an international comparison of the views of pregnant women and health professionals.

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Authors
Hill, Melissa
Johnson, Jo-Ann
Langlois, Sylvie
Lee, Hyun
Winsor, Stephanie
Dineley, Brigid
Horniachek, Marisa
Lalatta, Faustina
Ronzoni, Luisa
Barrett, Angela N
Advani, Henna V
Choolani, Mahesh
Rabinowitz, Ron
Pajkrt, Eva
van Schendel, Rachèl V
Henneman, Lidewij
Rommers, Wieke
Bilardo, Caterina M
Rendeiro, Paula
Ribeiro, Maria João
Rocha, José
Bay Lund, Ida Charlotte
Petersen, Olav B
Becher, Naja
Vogel, Ida
Stefánsdottir, Vigdis
Ingvarsdottir, Sigrun
Gottfredsdottir, Helga
Morris, Stephen
Chitty, Lyn S
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Issue Date
2016-07

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Preferences for prenatal tests for Down syndrome: an international comparison of the views of pregnant women and health professionals. 2016, 24 (7):968-75 Eur. J. Hum. Genet.
Abstract
Non-invasive prenatal testing is increasingly available worldwide and stakeholder viewpoints are essential to guide implementation. Here we compare the preferences of women and health professionals from nine different countries towards attributes of non-invasive and invasive prenatal tests for Down syndrome. A discrete choice experiment was used to obtain participants' stated preference for prenatal tests that varied according to four attributes: accuracy, time of test, risk of miscarriage, and type of information. Pregnant women and health professionals were recruited from Canada, Denmark, Iceland, Israel, Italy, the Netherlands, Portugal, Singapore, and the United Kingdom. A total of 2666 women's and 1245 health professionals' questionnaires were included in the analysis. Differences in preferences were seen between women and health professionals within and between countries. Overall, women placed greater emphasis on test safety and comprehensive information than health professionals, who emphasised accuracy and early testing. Differences between women's and health professionals' preferences are marked between countries. Varied approaches to implementation and service delivery are therefore needed and individual countries should develop guidelines appropriate for their own social and screening contexts.
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To access publisher's full text version of this article click on the hyperlink at the bottom of the page
Additional Links
http://dx.doi.org/ 10.1038/ejhg.2015.249
http://www.nature.com/ejhg/journal/v24/n7/pdf/ejhg2015249a.pdf
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Archived with thanks to European journal of human genetics : EJHG
ae974a485f413a2113503eed53cd6c53
10.1038/ejhg.2015.249
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English Journal Articles (Peer Reviewed)

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