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dc.contributor.authorOlafsson, Andri Snaer
dc.contributor.authorSigurjonsdottir, Helga Agusta
dc.date.accessioned2016-08-18T10:08:07Z
dc.date.available2016-08-18T10:08:07Z
dc.date.issued2016-01
dc.identifier.citationIncreasing Prevalence of Addison Disease: Results From a Nationwide Study. 2016, 22 (1):30-5 Endocr Practen
dc.identifier.issn1530-891X
dc.identifier.pmid26437215
dc.identifier.doi10.4158/EP15754.OR
dc.identifier.urihttp://hdl.handle.net/2336/618523
dc.descriptionTo access publisher's full text version of this article click on the hyperlink at the bottom of the pageen
dc.description.abstractPrimary adrenal insufficiency is a life-threatening endocrine disease unless properly treated. However, few studies on the prevalence, concomitances of the disease, and prescribing of drugs have been published. The goal of the study was to establish the prevalence of primary adrenal insufficiency in Iceland and additionally, to study the most common concomitant diseases in patients with primary adrenal insufficiency, as well as the mode of glucocorticoid replacement therapies.
dc.description.abstractTo achieve this, the medical records of all patients in Iceland who had received the International Classification of Diseases and Related Health Problems, 10th Revision, diagnosis code E27, were evaluated for true primary adrenal insufficiency. Additionally, these records were evaluated for concomitant diseases, as well as the mode of glucocorticoid replacement therapy. The study covered the whole population of Iceland over 18 years of age. It was thus a nationwide study. The records were retrieved from large hospitals and clinics and every practicing specialist in endocrinology.
dc.description.abstractPrimary adrenal insufficiency was found in 53 individuals, 26 women and 27 men, yielding a prevalence of 22.1 per 100,000 population. Hypothyroidism was by far the most common concomitant disease. Most patients had their glucocorticoid deficiency replaced with short-acting glucocorticoids.
dc.description.abstractThe prevalence of primary adrenal insufficiency in Iceland is higher than in earlier reports, with comorbidities being in line with recent studies. Treatment is according to the latest protocols.
dc.language.isoenen
dc.publisherAmer Assoc Clinical Endocrinologistsen
dc.relation.urlhttp://dx.doi.org/ 10.4158/EP15754.ORen
dc.rightsArchived with thanks to Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologistsen
dc.subjectHjarta- og æðasjúkdómaren
dc.subjectAldraðiren
dc.subjectHormónameðferðen
dc.subjectEND12
dc.subject.meshAddison Diseaseen
dc.subject.meshAdulten
dc.subject.meshAgeden
dc.subject.meshCardiovascular Diseasesen
dc.subject.meshCross-Sectional Studiesen
dc.subject.meshFemaleen
dc.subject.meshHormone Replacement Therapyen
dc.subject.meshHumansen
dc.subject.meshHydrocortisoneen
dc.subject.meshIcelanden
dc.subject.meshMaleen
dc.subject.meshMiddle Ageden
dc.subject.meshPrevalenceen
dc.titleIncreasing Prevalence of Addison Disease: Results From a Nationwide Studyen
dc.typeArticleen
dc.contributor.department[ 1 ] Univ Iceland, Fac Med, Reykjavik, Iceland [ 2 ] Landspitali Natl Univ Hosp, Dept Endocrinol, IS-108 Reykjavik, Iceland   Organization-Enhanced Name(s)      Landspitali National University Hospitalen
dc.identifier.journalEndocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologistsen
dc.rights.accessClosed - Lokaðen
html.description.abstractPrimary adrenal insufficiency is a life-threatening endocrine disease unless properly treated. However, few studies on the prevalence, concomitances of the disease, and prescribing of drugs have been published. The goal of the study was to establish the prevalence of primary adrenal insufficiency in Iceland and additionally, to study the most common concomitant diseases in patients with primary adrenal insufficiency, as well as the mode of glucocorticoid replacement therapies.
html.description.abstractTo achieve this, the medical records of all patients in Iceland who had received the International Classification of Diseases and Related Health Problems, 10th Revision, diagnosis code E27, were evaluated for true primary adrenal insufficiency. Additionally, these records were evaluated for concomitant diseases, as well as the mode of glucocorticoid replacement therapy. The study covered the whole population of Iceland over 18 years of age. It was thus a nationwide study. The records were retrieved from large hospitals and clinics and every practicing specialist in endocrinology.
html.description.abstractPrimary adrenal insufficiency was found in 53 individuals, 26 women and 27 men, yielding a prevalence of 22.1 per 100,000 population. Hypothyroidism was by far the most common concomitant disease. Most patients had their glucocorticoid deficiency replaced with short-acting glucocorticoids.
html.description.abstractThe prevalence of primary adrenal insufficiency in Iceland is higher than in earlier reports, with comorbidities being in line with recent studies. Treatment is according to the latest protocols.


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