Throat Infections are Associated with Exacerbation in a Substantial Proportion of Patients with Chronic Plaque Psoriasis.
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Your vote was cast
Thank you for your feedback
Thank you for your feedback
AuthorsThorleifsdottir, Ragna H
Eysteinsdóttir, Jenna H
Olafsson, Jón H
Sigurdsson, Martin I
MetadataShow full item record
CitationThroat Infections are Associated with Exacerbation in a Substantial Proportion of Patients with Chronic Plaque Psoriasis. 2016, 96 (6):788-91 Acta Derm. Venereol.
AbstractStreptococcal throat infections are known to trigger or exacerbate psoriasis, and several studies support the benefit of tonsillectomy. To evaluate the potential of tonsillectomy as a treatment, we used a retrospective study-specific questionnaire to assess the proportion of psoriasis patients with sore throat-associated psoriasis exacerbations. Our survey sampled 275 psoriasis patients. Of patients with plaque psoriasis, 42% reported sore throat-associated psoriasis exacerbations, and of patients with confirmed streptococcal infections, 72% reported aggravation. Notably, women and patients with early onset psoriasis were more likely to report psoriasis exacerbation after a sore throat (p < 0.001, p = 0.046, respectively). Other psoriasis aggravation factors were more common in patients with sore throat-associated exacerbations (p < 0.01). Of tonsillectomized patients, 49% reported subsequent improvement and had more frequent sore throat-associated aggravation of psoriasis than patients who did not improve after tonsillectomy (p = 0.015). These findings suggest a closer association between sore throats, streptococcal throat infections and plaque psoriasis than reported previously.
DescriptionTo access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Files. This article is open access.
RightsArchived with thanks to Acta dermato-venereologica
- Streptococcal throat infections and exacerbation of chronic plaque psoriasis: a prospective study.
- Authors: Gudjonsson JE, Thorarinsson AM, Sigurgeirsson B, Kristinsson KG, Valdimarsson H
- Issue date: 2003 Sep
- HLA-Cw6 homozygosity in plaque psoriasis is associated with streptococcal throat infections and pronounced improvement after tonsillectomy: A prospective case series.
- Authors: Thorleifsdottir RH, Sigurdardottir SL, Sigurgeirsson B, Olafsson JH, Petersen H, Sigurdsson MI, Gudjonsson JE, Johnston A, Valdimarsson H
- Issue date: 2016 Nov
- Antistreptococcal interventions for guttate and chronic plaque psoriasis.
- Authors: Owen CM, Chalmers RJ, O'Sullivan T, Griffiths CE
- Issue date: 2000
- WITHDRAWN: Antistreptococcal interventions for guttate and chronic plaque psoriasis.
- Authors: Owen CM, Chalmers R, O'Sullivan T, Griffiths CE
- Issue date: 2019 Mar 6
- Tonsillectomy Versus Watchful Waiting for Recurrent Throat Infection: A Systematic Review.
- Authors: Morad A, Sathe NA, Francis DO, McPheeters ML, Chinnadurai S
- Issue date: 2017 Feb