Renal recovery and long-term survival following acute kidney injury after coronary artery surgery: a nationwide study.
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Your vote was cast
Thank you for your feedback
Thank you for your feedback
MetadataShow full item record
CitationRenal recovery and long-term survival following acute kidney injury after coronary artery surgery: a nationwide study. 2016, 60 (9):1230-40 Acta Anaesthesiol Scand
AbstractAcute kidney injury (AKI) is a relatively common complication following CABG and is associated with adverse outcomes. Nonetheless, we hypothesized that the majority of patients make a good long-term recovery of their renal function. We studied the incidence and risk factors of AKI together with renal recovery and long-term survival in patients who developed AKI following CABG.
This nationwide study examined AKI among 1754 consecutive patients undergoing CABG in 2001-2013. AKI was defined according to the KDIGO criteria.
Postoperatively 184 (11%) patients developed AKI; 121 (7%), 27 (2%), and 36 (2%) at stages 1, 2, and 3, respectively. AKI was an independent risk factor for chronic kidney disease (CKD) and AKI patients had worse post-operative outcomes. Lower pre-operative glomerular filtration rate, higher EuroSCORE and BMI, diabetes, reoperation, and units of red blood cells transfused were independent risk factors of AKI. At post-operative day 10, renal recovery rates, defined as serum creatinine ratio <1.25 of baseline, were 96 (95% CI 91-99%), 78 (95% CI 53-90%), and 94% (95% CI 77-98%) for AKI stages 1, 2, and 3, respectively. Long-term survival was predicted by AKI with 10-year survival of patients without AKI being 76% and those with AKI stages 1, 2, and 3 being 63%, 56%, and 49%, respectively (P < 0.001).
Depending on the severity of the initial AKI, 78-97% of patients made good recovery of their kidney function. However, AKI was significantly linked to progression to CKD and long-term survival remained markedly affected by the severity of the initial kidney injury.
DescriptionTo access publisher's full text version of this article click on the hyperlink at the bottom of the page
RightsArchived with thanks to Acta anaesthesiologica Scandinavica
- Postoperative acute kidney injury defined by RIFLE criteria predicts early health outcome and long-term survival in patients undergoing redo coronary artery bypass graft surgery.
- Authors: Zakkar M, Bruno VD, Guida G, Angelini GD, Chivasso P, Suleiman MS, Bryan AJ, Ascione R
- Issue date: 2016 Jul
- Incidence, dynamics, and prognostic value of acute kidney injury for death after cardiac surgery.
- Authors: Dardashti A, Ederoth P, Algotsson L, Brondén B, Bjursten H
- Issue date: 2014 Feb
- Risk Factors for Long-Term Mortality and Progressive Chronic Kidney Disease Associated With Acute Kidney Injury After Cardiac Surgery.
- Authors: Xu JR, Zhu JM, Jiang J, Ding XQ, Fang Y, Shen B, Liu ZH, Zou JZ, Liu L, Wang CS, Ronco C, Liu H, Teng J
- Issue date: 2015 Nov
- Acute Kidney Injury Recovery Pattern and Subsequent Risk of CKD: An Analysis of Veterans Health Administration Data.
- Authors: Heung M, Steffick DE, Zivin K, Gillespie BW, Banerjee T, Hsu CY, Powe NR, Pavkov ME, Williams DE, Saran R, Shahinian VB, Centers for Disease Control and Prevention CKD Surveillance Team.
- Issue date: 2016 May
- Short-term and long-term outcomes of acute kidney injury after lung transplantation.
- Authors: Wehbe E, Brock R, Budev M, Xu M, Demirjian S, Schreiber MJ Jr, Stephany B
- Issue date: 2012 Mar