Show simple item record

dc.contributor.authorJonsdottir, Gudbjörgen
dc.contributor.authorGudmundsson, Jonen
dc.contributor.authorBirgisson, Gudjonen
dc.contributor.authorSigurjonsdottir, Helga Agustaen
dc.date.accessioned2017-02-06T13:48:53Z
dc.date.available2017-02-06T13:48:53Z
dc.date.issued2016-11-23
dc.identifier.citationPrimary aldosteronism: from case detection to histopathology with up to 6 years of follow-up. 2016 J Clin Hypertens (Greenwich)en
dc.identifier.citationJournal of Clinical Hypertension 2017,19(4):424-430
dc.identifier.issn1751-7176
dc.identifier.pmid27878955
dc.identifier.doi10.1111/jch.12947
dc.identifier.urihttp://hdl.handle.net/2336/620104
dc.descriptionNeðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/OpenTo access publisher's full text version of this article click on the hyperlink at the bottom of the pageen
dc.description.abstractThe authors aimed to investigate the clinical characteristics, accuracy of diagnostic tests, and long-term outcomes after interventions in patients diagnosed with primary aldosteronism (PA) in Iceland throughout 5 years. A retrospective chart review was performed for all patients diagnosed with PA during the years 2007-2011 at Landspitali Hospital in Iceland, a referral center for the whole country. Workup after detection included salt loading test, positional test, computed tomography, and adrenal vein sampling. Patients with unilateral disease were offered treatment with adrenalectomy. A total of 33 patients were diagnosed with PA during the study period: 17 patients with bilateral disease and 16 with unilateral disease. Results from salt loading test were positive in 90% of patients. In patients with adenoma, 36% were responsive on their positional test and computed tomography scan showed a nodule in 73%. All patients with unilateral disease had a lateralization index ≥3. After surgery, patients had lower systolic blood pressure (P<.001) and number of hypertensive medications (P<.01).
dc.description.sponsorshipLandspitali University Hospital Research Funden
dc.language.isoenen
dc.publisherWiley Periodicals Inc.en
dc.relation.urlhttp://onlinelibrary.wiley.com/doi/10.1111/jch.12947/epdfen
dc.rightsArchived with thanks to Journal of clinical hypertension (Greenwich, Conn.)en
dc.subjectEfnaskipta- og innkirtlalækningaren
dc.subjectInnkirtlasjúkdómaren
dc.subjectEND12en
dc.subjectDAI12en
dc.subjectSAM12en
dc.subject.meshHyperaldosteronismen
dc.subject.meshTreatment Outcomeen
dc.titlePrimary aldosteronism: from case detection to histopathology with up to 6 years of follow-up.en
dc.typeArticleen
dc.contributor.department1Faculty of Medicine, University of Iceland, Reykjavik, Iceland. 2Division of Interventional Radiology, Department of Radiology, Landspitali University Hospital, Reykjavik, Iceland. 3Department of Surgery, Landspitali University Hospital, Reykjavik, Iceland. 4Division of Endocrinology, Department of Medicine, Landspitali University Hospital, Reykjavik, Iceland.en
dc.identifier.journalJournal of clinical hypertension (Greenwich, Conn.)en
dc.rights.accessNational Consortium - Landsaðganguren
html.description.abstractThe authors aimed to investigate the clinical characteristics, accuracy of diagnostic tests, and long-term outcomes after interventions in patients diagnosed with primary aldosteronism (PA) in Iceland throughout 5 years. A retrospective chart review was performed for all patients diagnosed with PA during the years 2007-2011 at Landspitali Hospital in Iceland, a referral center for the whole country. Workup after detection included salt loading test, positional test, computed tomography, and adrenal vein sampling. Patients with unilateral disease were offered treatment with adrenalectomy. A total of 33 patients were diagnosed with PA during the study period: 17 patients with bilateral disease and 16 with unilateral disease. Results from salt loading test were positive in 90% of patients. In patients with adenoma, 36% were responsive on their positional test and computed tomography scan showed a nodule in 73%. All patients with unilateral disease had a lateralization index ≥3. After surgery, patients had lower systolic blood pressure (P<.001) and number of hypertensive medications (P<.01).


This item appears in the following Collection(s)

Show simple item record