• English
    • íslenska
  • English 
    • English
    • íslenska
  • Login
View Item 
  •   Home
  • Journal Articles, Peer Reviewed (Ritrýndar vísindagreinar)
  • English Journal Articles (Peer Reviewed)
  • View Item
  •   Home
  • Journal Articles, Peer Reviewed (Ritrýndar vísindagreinar)
  • English Journal Articles (Peer Reviewed)
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Browse

All of HirslaCommunitiesAuthorsTitleSubjectsSubject (MeSH)Issue DateJournalThis CollectionAuthorsTitleSubjectsSubject (MeSH)Issue DateJournal

My Account

LoginRegister

Local Links

FAQ - (Icelandic)FAQ - (English)Hirsla LogosAbout LandspitaliLSH Home PageLibrary HomeIcelandic Journals

Statistics

Display statistics

Lobectomy for non-small cell lung carcinoma: a nationwide study of short- and long-term survival.

  • CSV
  • RefMan
  • EndNote
  • BibTex
  • RefWorks
Average rating
 
   votes
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item. When enough users have cast their vote on this item, the average rating will also be shown.
Star rating
 
Your vote was cast
Thank you for your feedback
Authors
Oskarsdottir, G N
Halldorsson, H
Sigurdsson, M I
Fridriksson, B M
Baldvinsson, K
Orrason, A W
Jonsson, S
Planck, M
Gudbjartsson, T
Issue Date
2017-03-21

Metadata
Show full item record
Citation
Lobectomy for non-small cell lung carcinoma: a nationwide study of short- and long-term survival. 2017:1-7 Acta Oncol
Abstract
Lobectomy is the standard curative treatment for non-small cell carcinoma (NSCLC) of the lung. Most studies on lobectomy have focused on short-term outcome and 30-day mortality. The aim of this study was to determine both short-term and long-term surgical outcome in all patients who underwent lobectomy for NSCLC in Iceland over a 24-year period.
The study involved 489 consecutive patients with NSCLC who underwent lobectomy with curative intent in Iceland, 1991-2014. Patient demographics, pTNM stage, rate of perioperative complications, and 30-day mortality were registered. Overall survival was analyzed with the Kaplan?Meier method. The Cox proportional hazards model was used to evaluate factors that were prognostic of overall mortality. To study trends in survival, the study period was divided into six 4-year periods. The median follow-up time was 42 months and no patients were lost to follow-up.
The average age of the patients was 67 years and 53.8% were female. The pTNM disease stage was IA in 148 patients (30.0%), IB in 125 patients (25.4%), IIA in 96 patients (19.5%), and IIB in 50 patients (10.1%), but 74 (15.0%) were found to be stage IIIA, most often diagnosed perioperatively. The total rate of major complications was 4.7%. Thirty-day mortality was 0.6% (three patients). One- and 5-year overall survival was 85.0% and 49.2%, respectively, with 3-year survival improving from 48.3% to 72.8% between the periods 1991-1994 and 2011-2014 (p = .0004). Advanced TNM stage and age were independent negative prognostic factors for all-cause mortality, and later calendar year and free surgical margins were independent predictors of improved survival.
The short-term outcome of lobectomy for NSCLC in this population-based study was excellent, as reflected in the low 30-day mortality and low rate of major complications. The long-term survival was acceptable and the overall 3-year survival had improved significantly during the study period.
Description
Efst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn
Additional Links
http://www.tandfonline.com/doi/pdf/10.1080/0284186X.2017.1304652?needAccess=true
Rights
Archived with thanks to Acta oncologica (Stockholm, Sweden)
ae974a485f413a2113503eed53cd6c53
10.1080/0284186X.2017.1304652
Scopus Count
Collections
English Journal Articles (Peer Reviewed)

entitlement

Related articles

  • Resection rate and outcome of pulmonary resections for non-small-cell lung cancer: a nationwide study from Iceland.
  • Authors: Thorsteinsson H, Alexandersson A, Oskarsdottir GN, Skuladottir R, Isaksson HJ, Jonsson S, Gudbjartsson T
  • Issue date: 2012 Jul
  • Robotic lobectomy for non-small cell lung cancer (NSCLC): long-term oncologic results.
  • Authors: Park BJ, Melfi F, Mussi A, Maisonneuve P, Spaggiari L, Da Silva RK, Veronesi G
  • Issue date: 2012 Feb
  • Sleeve lobectomy as an alternative to pneumonectomy in patients with operable lung cancer.
  • Authors: Kasprzyk M, Dyszkiewicz W, Piwkowski C, Brudlo M, Galecki B, Gabryel P, Gasiorowski L
  • Issue date: 2013
  • [Factors predictive of survival after lobectomy for non-small cell lung cancer in Iceland during 1999-2008].
  • Authors: Oskarsdóttir GN, Skúladóttir R, Isaksson HJ, Jónsson S, Thorsteinsson H, Gudbjartsson T
  • Issue date: 2010 Apr
  • Wedge resection verses lobectomy for stage 1 non-small-cell lung cancer.
  • Authors: Warwick R, Mediratta N, Shackcloth M, Page R, McShane J, Shaw M, Poullis M
  • Issue date: 2013 Oct

DSpace software (copyright © 2002 - 2022)  DuraSpace
Quick Guide | Contact Us
Open Repository is a service operated by 
Atmire NV
 

Export search results

The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.