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The Scandinavian Sarcoma Group Central Register: 6,000 patients after 25 years of monitoring of referral and treatment of extremity and trunk wall soft-tissue sarcoma.

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Authors
Trovik, Clement
Bauer, Henrik C F
Styring, Emelie
Sundby Hall, Kirsten
Vult Von Steyern, Fredrik
Eriksson, Sigvard
Johansson, Ingela
Sampo, Mika
Laitinen, Minna
Kalén, Anders
Jónsson, Halldór
Jebsen, Nina
Eriksson, Mikael
Tukiainen, Erkki
Wall, Najme
Zaikova, Olga
Sigurðsson, Helgi
Lehtinen, Tuula
Bjerkehagen, Bodil
Skorpil, Mikael
Egil Eide, Geir
Johansson, Elisabeth
Alvegard, Thor A
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Issue Date
2017-06

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The Scandinavian Sarcoma Group Central Register: 6,000 patients after 25 years of monitoring of referral and treatment of extremity and trunk wall soft-tissue sarcoma. 2017, 88 (3):341-347 Acta Orthop
Abstract
Purpose - We wanted to examine the potential of the Scandinavian Sarcoma Group (SSG) Central Register, and evaluate referral and treatment practice for soft-tissue sarcomas in the extremities and trunk wall (STS) in the Nordic countries. Background - Based on incidence rates from the literature, 8,150 (7,000-9,300) cases of STS of the extremity and trunk wall should have been diagnosed in Norway, Finland, Iceland, and Sweden from 1987 through 2011. The SSG Register has 6,027 cases registered from this period, with 5,837 having complete registration of key variables. 10 centers have been reporting to the Register. The 5 centers that consistently report treat approximately 90% of the cases in their respective regions. The remaining centers have reported all the patients who were treated during certain time periods, but not for the entire 25-year period. Results - 59% of patients were referred to a sarcoma center untouched, i.e. before any attempt at open biopsy. There was an improvement from 52% during the first 5 years to 70% during the last 5 years. 50% had wide or better margins at surgery. Wide margins are now achieved less often than 20 years ago, in parallel with an increase in the use of radiotherapy. For the centers that consistently report, 97% of surviving patients are followed for more than 4 years. Metastasis-free survival (MFS) increased from 67% to 73% during the 25-year period. Interpretation - The Register is considered to be representative of extremity and trunk wall sarcoma disease in the population of Scandinavia, treated at the reporting centers. There were no clinically significant differences in treatment results at these centers.
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434606/pdf/iort-88-341.pdf
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Archived with thanks to Acta orthopaedica
ae974a485f413a2113503eed53cd6c53
10.1080/17453674.2017.1293441
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