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dc.contributor.authorPedersen, Marie
dc.contributor.authorOlsen, Sjurdur F
dc.contributor.authorHalldorsson, Thorhallur I
dc.contributor.authorZhang, Cuilin
dc.contributor.authorHjortebjerg, Dorrit
dc.contributor.authorKetzel, Matthias
dc.contributor.authorGrandström, Charlotta
dc.contributor.authorSørensen, Mette
dc.contributor.authorDamm, Peter
dc.contributor.authorLanghoff-Roos, Jens
dc.contributor.authorRaaschou-Nielsen, Ole
dc.date.accessioned2017-11-23T13:20:52Z
dc.date.available2017-11-23T13:20:52Z
dc.date.issued2017-11
dc.date.submitted2017
dc.identifier.citationGestational diabetes mellitus and exposure to ambient air pollution and road traffic noise: A cohort study. 2017, 108:253-260 Environ Inten
dc.identifier.issn1873-6750
dc.identifier.pmid28892786
dc.identifier.doi10.1016/j.envint.2017.09.003
dc.identifier.urihttp://hdl.handle.net/2336/620359
dc.descriptionTo access publisher's full text version of this article click on the hyperlink belowen
dc.description.abstractRoad traffic is a main source of air pollution and noise. Both exposures have been associated with type 2 diabetes, but associations with gestational diabetes mellitus (GDM) have been studied less.
dc.description.abstractWe aimed to examine single and joint associations of exposure to air pollution and road traffic noise on GDM in a prospective cohort.
dc.description.abstractWe identified GDM cases from self-reports and hospital records, using two different criteria, among 72,745 singleton pregnancies (1997-2002) from the Danish National Birth Cohort. We modeled nitrogen dioxide (NO2) and noise from road traffic (Lden) exposure at all pregnancy addresses.
dc.description.abstractAccording to the two diagnostic criteria: the Danish clinical guidelines, which was our main outcome, and the WHO standard during recruitment period, a total of 565 and 210 women, respectively, had GDM. For both exposures no risk was evident for the common Danish criterion of GDM. A 10-μg/m(3) increase in NO2 exposure during first trimester was, however, associated with an increased risk of WHO-GDM (adjusted odds ratio (OR)=1.24; 95% confidence interval (CI): 1.03, 1.49). The corresponding OR associated with a 10-dB higher road traffic noise level was 1.15 (0.94 to 1.18). In mutually adjusted models the OR for NO2 remained similar 1.22 (0.98, 1.53) whereas that for road traffic noise decreased to 1.03 (0.80, 1.32). Significant associations were also observed for exposure averaged over the 2nd and 3rd trimesters and the full pregnancy.
dc.description.abstractNo risk was evident for the common Danish criterion of GDM. NO2 was associated with higher risk for GDM according to the WHO criterion, which might be due to selection bias.
dc.language.isoenen
dc.publisherPergamon-Elsevier Science Ltd.en
dc.relation.urlhttps://ac.els-cdn.com/S0160412017304865/1-s2.0-S0160412017304865-main.pdf?_tid=c712d1d2-d04f-11e7-88d7-00000aacb35f&acdnat=1511442852_12d7546f2a1f2916c99982da6d6975aben
dc.rightsArchived with thanks to Environment internationalen
dc.subjectSykursýkien
dc.subjectMeðgangaen
dc.subjectMengunen
dc.subjectHávaðamengunen
dc.subjectLoftmengunen
dc.subjectNUR12en
dc.subject.meshDiabetes, Gestationalen
dc.subject.meshPregnancyen
dc.subject.meshAir Pollutionen
dc.subject.meshNoiseen
dc.subject.meshAutomobilesen
dc.titleGestational diabetes mellitus and exposure to ambient air pollution and road traffic noise: A cohort study.en
dc.typeArticleen
dc.contributor.department[ 1 ] Univ Copenhagen, Dept Publ Hlth, Ctr Epidemiol & Screening, Oster Farimagsgade 5A, DK-1014 Copenhagen K, Denmark [ 2 ] Danish Canc Soc, Res Ctr, Strandboulevarden 49, DK-2100 Copenhagen O, Denmark [ 3 ] Statens Serum Inst, Dept Epidemiol Res, Ctr Fetal Programming, Artillerivej 5, DK-2300 Copenhagen S, Denmark Show the Organization-Enhanced name(s) [ 4 ] Harvard Sch Publ Hlth, Dept Nutr, 677 Huntington Ave, Boston, MA 02115 USA Show the Organization-Enhanced name(s) [ 5 ] Univ Iceland, Fac Food Sci & Nutr, Saemundargata 2, IS-101 Reykjavik, Iceland Show the Organization-Enhanced name(s) [ 6 ] Landspitali Univ Hosp, Unit Nutr Res, Eiriksgata 29, Reykjavik, Iceland Show the Organization-Enhanced name(s) [ 7 ] Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Div Intramural Populat Hlth Res, 6100 Execut Blvd,Rm 7B03, Rockville, MD 20852 USA Show the Organization-Enhanced name(s) [ 8 ] Aarhus Univ, Dept Environm Sci, Frederiksborgvej 399, DK-4000 Roskilde, Denmark Show the Organization-Enhanced name(s) [ 9 ] Rigshosp, Copenhagen Univ Hosp, Ctr Pregnant Women Diabet, Blegdamsvej 9, DK-2100 Copenhagen O, Denmark Show the Organization-Enhanced name(s) [ 10 ] Univ Copenhagen, Inst Clin Med, Fac Hlth & Med Sci, Blegdamsvej 3B, DK-2200 Copenhagen N, Denmark [ 11 ] Rigshosp, Dept Obstet, Blegdamsvej 9, DK-2100 Copenhagen O, Denmarken
dc.identifier.journalEnvironment internationalen
dc.rights.accessNational Consortium - Landsaðganguren
html.description.abstractRoad traffic is a main source of air pollution and noise. Both exposures have been associated with type 2 diabetes, but associations with gestational diabetes mellitus (GDM) have been studied less.
html.description.abstractWe aimed to examine single and joint associations of exposure to air pollution and road traffic noise on GDM in a prospective cohort.
html.description.abstractWe identified GDM cases from self-reports and hospital records, using two different criteria, among 72,745 singleton pregnancies (1997-2002) from the Danish National Birth Cohort. We modeled nitrogen dioxide (NO2) and noise from road traffic (Lden) exposure at all pregnancy addresses.
html.description.abstractAccording to the two diagnostic criteria: the Danish clinical guidelines, which was our main outcome, and the WHO standard during recruitment period, a total of 565 and 210 women, respectively, had GDM. For both exposures no risk was evident for the common Danish criterion of GDM. A 10-μg/m(3) increase in NO2 exposure during first trimester was, however, associated with an increased risk of WHO-GDM (adjusted odds ratio (OR)=1.24; 95% confidence interval (CI): 1.03, 1.49). The corresponding OR associated with a 10-dB higher road traffic noise level was 1.15 (0.94 to 1.18). In mutually adjusted models the OR for NO2 remained similar 1.22 (0.98, 1.53) whereas that for road traffic noise decreased to 1.03 (0.80, 1.32). Significant associations were also observed for exposure averaged over the 2nd and 3rd trimesters and the full pregnancy.
html.description.abstractNo risk was evident for the common Danish criterion of GDM. NO2 was associated with higher risk for GDM according to the WHO criterion, which might be due to selection bias.


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