Acute kidney injury following coronary angiography: a nationwide study of incidence, risk factors and long-term outcomes.
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Long, Thorir E
Sigurdsson, Gisli H
Indridason, Olafur S
Gudmundsdottir, Ingibjorg J
Sigurdsson, Martin I
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CitationAcute kidney injury following coronary angiography: a nationwide study of incidence, risk factors and long-term outcomes. 2018, 31(5):721-730 Journal of nephrology
AbstractWe studied the incidence and risk factors of acute kidney injury (AKI) following coronary angiography (CA) and examined short- and long-term outcomes of patients who developed AKI, including progression of chronic kidney disease (CKD). This was a retrospective study of all patients undergoing CA in Iceland from 2008 to 2015, with or without percutaneous coronary intervention. All procedures were performed with iso-osmolar contrast. AKI was defined according to the SCr component of the KDIGO criteria. Patients without post-procedural SCr were assumed to be free of AKI. Incident CKD was defined as 90-day sustained estimated glomerular filtration rate (eGFR) < 60 mL/min/1.73 m AKI was detected in 231 of 13,561 cases (1.7%). There was an interaction between contrast dose and preexisting kidney function, where the risk for AKI was only significant at a dose > 150 mL in patients with baseline eGFR < 45 mL/min/1.73 m For iso-osmolar contrast, the risk of AKI related to contrast dose was evident for higher amount of contrast in patients with baseline eGFR < 45 mL/min/1.73 m
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