Prevalence estimates and risk factors for early childhood wheeze across Europe: the EuroPrevall birth cohort.
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Your vote was cast
Thank you for your feedback
Thank you for your feedback
Grimshaw, Kate E
Kowalski, Marek L
Papadopoulos, Nikolaos G
Sigurdardottir, Sigurveig T
Sprikkelman, Aline B
Mills, E N Clare
MetadataShow full item record
CitationPrevalence estimates and risk factors for early childhood wheeze across Europe: the EuroPrevall birth cohort. 2018, 73(11):1049-1061 Thorax
AbstractPreschool wheeze is an important problem worldwide. No comparative population-based studies covering different countries have previously been undertaken. To assess the prevalence of early childhood wheeze across Europe and evaluate risk factors focusing on food allergy, breast feeding and smoke exposure. Infants from nine countries were recruited into the EuroPrevall birth cohort. At 12 and 24 months, data on wheeze, allergic signs/symptoms, feeding, smoke exposure, infections and day care attendance were collected using questionnaires. Poisson regression was used to assess risk factors for wheeze. 12 049 infants were recruited. Data from the second year of life were available in 8805 (73.1%). The prevalence of wheeze in the second year of life ranged from <2% in Lodz (Poland) and Vilnius (Lithuania) to 13.1% (95% CI 10.7% to 15.5%) in Southampton (UK) and 17.2% (95% CI 15.0% 19.5%) in Reykjavik (Iceland). In multivariable analysis, frequent lower respiratory tract infections in the first and second years of life (incidence rate ratio (IRR) 1.9 (95% CI 1.3 to 2.6) and 2.5 (95% CI 1.9 to3.4), respectively), postnatal maternal smoking (IRR 1.6, 95% CI 1.1 to 2.4), day care attendance (IRR 1.6, 95% CI 1.1 to 2.5) and male gender (IRR 1.3, 95% CI 1.0 to 1.7) were associated with wheeze. The strength of their association with wheeze differed between countries. Food allergy and breast feeding were not independently associated with wheeze.
DescriptionTo access publisher's full text version of this article click on the hyperlink below
- Maternal use of folic acid supplements during pregnancy, and childhood respiratory health and atopy.
- Authors: Bekkers MB, Elstgeest LE, Scholtens S, Haveman-Nies A, de Jongste JC, Kerkhof M, Koppelman GH, Gehring U, Smit HA, Wijga AH
- Issue date: 2012 Jun
- Early life factors associated with incidence of physician-diagnosed asthma in preschool children: results from the Canadian Early Childhood Development cohort study.
- Authors: Midodzi WK, Rowe BH, Majaesic CM, Saunders LD, Senthilselvan A
- Issue date: 2010 Feb
- Preconceptional exposure to oral contraceptive pills and the risk of wheeze, asthma and rhinitis in children.
- Authors: Yamamoto-Hanada K, Futamura M, Yang L, Shoda T, Narita M, Kobayashi F, Saito H, Ohya Y
- Issue date: 2016 Jul
- Early-life risk factors for childhood wheeze phenotypes in a high-risk birth cohort.
- Authors: Lodge CJ, Zaloumis S, Lowe AJ, Gurrin LC, Matheson MC, Axelrad C, Bennett CM, Hill DJ, Hosking CS, Svanes C, Abramson MJ, Allen KJ, Dharmage SC
- Issue date: 2014 Feb
- Early life risk factors for current wheeze, asthma, and bronchial hyperresponsiveness at 10 years of age.
- Authors: Arshad SH, Kurukulaaratchy RJ, Fenn M, Matthews S
- Issue date: 2005 Feb