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DPYD, TYMS and MTHFR Genes Polymorphism Frequencies in a Series of Turkish Colorectal Cancer Patients.

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Authors
Amirfallah, Arsalan
Kocal, Gizem Calibasi
Unal, Olcun Umit
Ellidokuz, Hulya
Oztop, Ilhan
Basbinar, Yasemin
Issue Date
2018-12-13

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DPYD, TYMS and MTHFR Genes Polymorphism Frequencies in a Series of Turkish Colorectal Cancer Patients. 2018, 8(4). pii: E45 J Pers Med
Abstract
Fluoropyrimidine-based chemotherapy is extensively used for the treatment of solid cancers, including colorectal cancer. However, fluoropyrimidine-driven toxicities are a major problem in the management of the disease. The grade and type of the toxicities depend on demographic factors, but substantial inter-individual variation in fluoropyrimidine-related toxicity is partly explained by genetic factors. The aim of this study was to investigate the effect of
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https://www.mdpi.com/2075-4426/8/4/45
ae974a485f413a2113503eed53cd6c53
10.3390/jpm8040045
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