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dc.contributor.authorMagnusdottir, Berglind A
dc.contributor.authorBaldursdottir, Maria B
dc.contributor.authorKalaitzakis, Evangelos
dc.contributor.authorBjörnsson, Einar S
dc.date.accessioned2019-05-16T14:06:40Z
dc.date.available2019-05-16T14:06:40Z
dc.date.issued2019-01
dc.date.submitted2019-05
dc.identifier.citationRisk factors for chronic and recurrent pancreatitis after first attack of acute pancreatitis. 2019, 54(1):87-94 Scand J Gastroenterolen_US
dc.identifier.issn1502-7708
dc.identifier.pmid30700163
dc.identifier.doi10.1080/00365521.2018.1550670
dc.identifier.urihttp://hdl.handle.net/2336/620901
dc.descriptionTo access publisher's full text version of this article click on the hyperlink belowen_US
dc.description.abstractTo study the outcome of acute pancreatitis and risk factors for recurrent and chronic pancreatitis in a population based cohort of patients with first-time acute pancreatitis. All patients with first-time acute pancreatitis from 2006-2015 in Iceland were retrospectively evaluated. Medical records were scrutinized and relevant data extracted. 1102 cases of first-time acute pancreatitis were identified: mean age 56yr, 46% female, 41% biliary, 21% alcohol, 26% idiopathic, 13% other causes, mean follow-up 4yr. 21% had ≥1 recurrent acute pancreatitis which was independently related to alcoholic (vs. biliary hazard ratio (HR) 2.29, 95% confidence interval (CI) 1.51-3.46), male gender (HR 1.48, 95%CI 1.08-2.04), and smoking (HR 1.62, 95%CI 1.15-2.28). 3.7% developed chronic pancreatitis. Independent predictors were recurrent acute pancreatitis (HR 8.79, 95%CI 3.94-19.62), alcoholic (vs. biliary HR 9.16, 95%CI 2.71-30.9), local complications (HR 4.77, 95%CI 1.93-11.79), and organ-failure (HR 2.86, 95%CI 1.10-7.42). Recurrent acute pancreatitis occurred in one-fifth of patients. Development of chronic pancreatitis was infrequent. Both recurrent acute pancreatitis and chronic pancreatitis were related to alcoholic acute pancreatitis, while recurrent acute pancreatitis was associated with smoking and male gender, and chronic pancreatitis to recurrent acute pancreatitis, organ-failure, and local complications.en_US
dc.language.isoenen_US
dc.publisherTaylor & Francisen_US
dc.relation.urlhttps://www.tandfonline.com/doi/full/10.1080/00365521.2018.1550670en_US
dc.subjectPancreasen_US
dc.subjectalcoholen_US
dc.subjectcholecystectomyen_US
dc.subjectgallstonesen_US
dc.subjectnatural historyen_US
dc.subjectBrisbólga
dc.subject.meshPancreatitisen_US
dc.subject.meshPancreatitis, Chronicen_US
dc.subject.meshPancreatitis, Alcoholicen_US
dc.titleRisk factors for chronic and recurrent pancreatitis after first attack of acute pancreatitis.en_US
dc.typeArticleen_US
dc.contributor.department1 a Faculty of Medicine , University of Iceland , Reykjavík , Iceland. 2 b Digestive Disease Center, Copenhagen University Hospital/Herlev, University of Copenhagen , Copenhagen , Denmark. 3 c Department of Gastroenterology , Landspitali University Hospital Reykjavik , Reykjavík , Iceland.en_US
dc.identifier.journalScandinavian journal of gastroenterologyen_US
dc.rights.accessLandspitali Access - LSH-aðganguren_US
dc.departmentcodeGAS12
dc.source.journaltitleScandinavian journal of gastroenterology


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