Average rating
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Star rating
Your vote was cast
Thank you for your feedback
Thank you for your feedback
Issue Date
2019-07
Metadata
Show full item recordOther Titles
Opioid overdose following voriconazole treatment – case reportCitation
Ópíóíðaeitrun í kjölfar vórikónazólmeðferðar. 2019, 105(7-8): 335-337Abstract
67 ára gömul kona, sem tók langverkandi ópíóíðalyf (oxýkódon) vegna langvarandi brjóstverkja, varð fyrir bráðri ópíóíðaeitrun eftir að hafin var meðferð með vórikónazóli. Vórikónazól er sveppalyf sem getur bælt virkni CYP3A4 sem er niðurbrotsensím í lifur og gegnir lykilhlutverki í umbroti ýmissa lyfja. Í þessu tilfelli jókst sermisstyrkur oxýkódons sem olli alvarlegri ópíóíðaeitrun.67-year-old female who was taking oxycodone due to chronic chest pain suffered from opioid overdose after starting treatment with voriconazole. Voriconazole is an antifungal that inhibits CYP3A4 activity in the liver. In the case reported herein, this led to higher plasma concentration of oxycodone which caused severe opioid overdose
Description
To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked DownloadAdditional Links
https://www.laeknabladid.is/tolublod/2019/07/08/nr/7097