Occupational exposures and incidence of chronic bronchitis and related symptoms over two decades: the European Community Respiratory Health Survey.
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Your vote was cast
Thank you for your feedback
Thank you for your feedback
Antó, Josep Maria
Gullón, José Antonio
Vega, Antonio Pereira
Raherison Semjen, Chantal
Mehta, Amar J
Blanc, Paul D
Buist, A Sonia
MetadataShow full item record
CitationOccupational exposures and incidence of chronic bronchitis and related symptoms over two decades: the European Community Respiratory Health Survey. 2019,76(4): 222-229 Occup Environ Med.
AbstractOBJECTIVES: Chronic bronchitis (CB) is an important chronic obstructive pulmonary disease (COPD)-related phenotype, with distinct clinical features and prognostic implications. Occupational exposures have been previously associated with increased risk of CB but few studies have examined this association prospectively using objective exposure assessment. We examined the effect of occupational exposures on CB incidence in the European Community Respiratory Health Survey. METHODS: Population samples aged 20-44 were randomly selected in 1991-1993, and followed up twice over 20 years. Participants without chronic cough or phlegm at baseline were analysed. Coded job histories during follow-up were linked to the ALOHA Job Exposure Matrix, generating occupational exposure estimates to 12 categories of chemical agents. Their association with CB incidence over both follow-ups was examined with Poisson models using generalised estimating equations. RESULTS: 8794 participants fulfilled the inclusion criteria, contributing 13 185 observations. Only participants exposed to metals had a higher incidence of CB (relative risk (RR) 1.70, 95% CI 1.16 to 2.50) compared with non-exposed to metals. Mineral dust exposure increased the incidence of chronic phlegm (RR 1.72, 95% CI 1.43 to 2.06). Incidence of chronic phlegm was increased in men exposed to gases/fumes and to solvents and in women exposed to pesticides. CONCLUSIONS: Occupational exposures are associated with chronic phlegm and CB, and the evidence is strongest for metals and mineral dust exposure. The observed differences between men and women warrant further investigation.
- Interaction of atopy and smoking on respiratory effects of occupational dust exposure: a general population-based study.
- Authors: de Meer G, Kerkhof M, Kromhout H, Schouten JP, Heederik D
- Issue date: 2004 Jun 2
- Occupational exposures and 20-year incidence of COPD: the European Community Respiratory Health Survey.
- Authors: Lytras T, Kogevinas M, Kromhout H, Carsin AE, Antó JM, Bentouhami H, Weyler J, Heinrich J, Nowak D, Urrutia I, Martinez-Moratalla J, Gullón JA, Pereira-Vega A, Raherison-Semjen C, Pin I, Demoly P, Leynaert B, Villani S, Gislason T, Svanes C, Holm M, Forsberg B, Norbäck D, Mehta AJ, Probst-Hensch N, Benke G, Jogi R, Torén K, Sigsgaard T, Schlünssen V, Olivieri M, Blanc PD, Vermeulen R, Garcia-Aymerich J, Jarvis D, Zock JP
- Issue date: 2018 Nov
- Lung function decline, chronic bronchitis, and occupational exposures in young adults.
- Authors: Sunyer J, Zock JP, Kromhout H, Garcia-Esteban R, Radon K, Jarvis D, Toren K, Künzli N, Norbäck D, d'Errico A, Urrutia I, Payo F, Olivieri M, Villani S, Van Sprundel M, Antó JM, Kogevinas M, Occupational Group of the European Community Respiratory Health Survey.
- Issue date: 2005 Nov 1
- [Effect of occupational exposure and smoking on spirometric tests and symptoms of chronic bronchitis].
- Authors: Kachel T
- Issue date: 2003
- Occupational exposure to pesticides are associated with fixed airflow obstruction in middle-age.
- Authors: Alif SM, Dharmage SC, Benke G, Dennekamp M, Burgess JA, Perret JL, Lodge CJ, Morrison S, Johns DP, Giles GG, Gurrin LC, Thomas PS, Hopper JL, Wood-Baker R, Thompson BR, Feather IH, Vermeulen R, Kromhout H, Walters EH, Abramson MJ, Matheson MC
- Issue date: 2017 Nov