Show simple item record

dc.contributor.authorJarlier, Vincent
dc.contributor.authorDiaz Högberg, Liselotte
dc.contributor.authorHeuer, Ole E
dc.contributor.authorCampos, José
dc.contributor.authorEckmanns, Tim
dc.contributor.authorGiske, Christian G
dc.contributor.authorGrundmann, Hajo
dc.contributor.authorJohnson, Alan P
dc.contributor.authorKahlmeter, Gunnar
dc.contributor.authorMonen, Jos
dc.contributor.authorPantosti, Annalisa
dc.contributor.authorRossolini, Gian Maria
dc.contributor.authorvan de Sande-Bruinsma, Nienke
dc.contributor.authorVatopoulos, Alkiviadis
dc.contributor.authorŻabicka, Dorota
dc.contributor.authorŽemličková, Helena
dc.contributor.authorMonnet, Dominique L
dc.contributor.authorSimonsen, Gunnar Skov
dc.date.accessioned2019-09-26T15:51:37Z
dc.date.available2019-09-26T15:51:37Z
dc.date.issued2019-01-01
dc.date.submitted2019-09
dc.identifier.citationStrong correlation between the rates of intrinsically antibiotic-resistant species and the rates of acquired resistance in Gram-negative species causing bacteraemia, EU/EEA, 2016. 2019, 24(33). doi: 10.2807/1560-7917.ES.2019.24.33.1800538 Euro Surveillen_US
dc.identifier.issn1560-7917
dc.identifier.pmid31431208
dc.identifier.doi10.2807/1560-7917.ES.2019.24.33.1800538
dc.identifier.urihttp://hdl.handle.net/2336/621080
dc.descriptionTo access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Downloaden_US
dc.description.abstractBackgroundAntibiotic resistance, either intrinsic or acquired, is a major obstacle for treating bacterial infections.AimOur objective was to compare the country-specific species distribution of the four Gram-negative species Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter species and the proportions of selected acquired resistance traits within these species.MethodWe used data reported for 2016 to the European Antimicrobial Resistance Surveillance Network (EARS-Net) by 30 countries in the European Union and European Economic Area.ResultsThe country-specific species distribution varied considerably. While E. coli accounted for 31.9% to 81.0% (median: 69.0%) of all reported isolates, the two most common intrinsically resistant species P. aeruginosa and Acinetobacter spp. combined (PSEACI) accounted for 5.5% to 39.2% of isolates (median: 10.1%). Similarly, large national differences were noted for the percentages of acquired non-susceptibility to third-generation cephalosporins, carbapenems and fluoroquinolones. There was a strong positive rank correlation between the country-specific percentages of PSEACI and the percentages of non-susceptibility to the above antibiotics in all four species (rho > 0.75 for 10 of the 11 pairs of variables tested).ConclusionCountries with the highest proportion of P. aeruginosa and Acinetobacter spp. were also those where the rates of acquired non-susceptibility in all four studied species were highest. The differences are probably related to national differences in antibiotic consumption and infection prevention and control routines.en_US
dc.language.isoenen_US
dc.publisherEuropean Centre for Disease Prevention and Control (ECDC)en_US
dc.relation.urlhttps://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2019.24.33.1800538en_US
dc.relation.urlhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702794/en_US
dc.subjectGram-negative bacillien_US
dc.subjectantibiotic resistanceen_US
dc.subjectantimicrobial resistanceen_US
dc.subjectbacterial infectionsen_US
dc.subjectbloodstream infectionen_US
dc.subjectSýklalyfjaónæmien_US
dc.subject.meshDrug Resistance, Bacterialen_US
dc.subject.meshGram-Negative Bacteriaen_US
dc.titleStrong correlation between the rates of intrinsically antibiotic-resistant species and the rates of acquired resistance in Gram-negative species causing bacteraemia, EU/EEA, 2016.en_US
dc.typeArticleen_US
dc.contributor.department1 Assistance Publique - Hôpitaux de Paris, Pitié-Salpêtrière hospital, Laboratoire de Bactériologie-Hygiène, Paris, France. 2 Sorbonne Universités (Paris 06) Inserm Centre d'Immunologie et des Maladies Infectieuses (CIMI), UMR 1135, Paris, France. 3 European Centre for Disease Prevention and Control, Solna, Sweden. 4 Reference and Research Laboratory on Antimicrobial Resistance, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain. 5 Robert Koch Institute, Department for Infectious Disease Epidemiology, Berlin, Germany. 6 Department of Clinical Microbiology, Karolinska University Hospital, Stockholm, Sweden. 7 Department of Laboratory Medicine, Karolinska Institute, Stockholm, Sweden. 8 Medical Center - University of Freiburg, Department for Infection Prevention and Hospital Epidemiology, Freiburg, Germany. 9 National Infection Service, Public Health England, London, United Kingdom. 10 Clinical Microbiology, Central Hospital, Växjö, Sweden. 11 National Institute for Public Health and the Environment, Bilthoven, the Netherlands. 12 Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy. 13 Microbiology and Virology Unit, Florence Careggi University Hospital, Florence, Italy. 14 Department of Experimental and Clinical Medicine, University of Florence, Italy. 15 Pan American Health Organization/World Health Organization (PAHO/ WHO), Washington DC, United States. 16 Department of Public Health Policy, School of Public Health, University of West Attica, Athens, Greece. 17 Department of Epidemiology and Clinical Microbiology, National Medicines Institute, Warsaw, Poland. 18 Department of Clinical Microbiology, Faculty of Medicine and University Hospital, Charles University, Hradec Kralove, Czech Republic. 19 National Institute of Public Health, National Reference Laboratory for Antibiotics, Prague, Czech Republic. 20 Research Group for Host-Microbe Interaction, Faculty of Health Sciences, UiT - The Arctic University of Norway, Tromsø, Norway. 21 Department of Microbiology and Infection Control, University Hospital of North Norway, Tromsø, Norway. 22 The members of the group are listed at the end of the article.en_US
dc.identifier.journalEurosurveillanceen_US
dc.rights.accessOpen Access - Opinn aðganguren_US
dc.departmentcodeBAC12
dc.source.journaltitleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
refterms.dateFOA2019-09-26T15:51:38Z


Files in this item

Thumbnail
Name:
Strong ....pdf
Size:
326.1Kb
Format:
PDF

This item appears in the following Collection(s)

Show simple item record