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dc.contributor.authorEinarsdottir, Anna B
dc.contributor.authorSveinsson, Olafur
dc.contributor.authorOlafsson, Elias
dc.date.accessioned2019-10-22T10:45:55Z
dc.date.available2019-10-22T10:45:55Z
dc.date.issued2019-09-30
dc.date.submitted2019-10
dc.identifier.citationSudden unexpected death in epilepsy. A nationwide population-based study. 2019, doi: 10.1111/epi.16349 Epilepsiaen_US
dc.identifier.issn1528-1167
dc.identifier.pmid31571204
dc.identifier.doi10.1111/epi.16349
dc.identifier.urihttp://hdl.handle.net/2336/621111
dc.descriptionTo access publisher's full text version of this article click on the hyperlink belowen_US
dc.description.abstractOBJECTIVE: The incidence of sudden unexpected death in epilepsy (SUDEP) varies between studies. We determined the incidence of SUDEP in the entire Icelandic population during a 20-year period. METHODS: All individuals in Iceland with epilepsy who died unexpectedly from January 1, 1991 through December 31, 2010 were included. Case ascertainment was based on autopsies, reimbursement for antiepileptic drugs, death certificates, information from neurologists, and medical records. The incidence of SUDEP was calculated according to the total number of residents in Iceland during the study period and an estimated epilepsy population of Iceland. RESULTS: We identified 37 individuals (26 men, 11 women) with definite SUDEP (n = 29), definite SUDEP plus (n = 4), and probable SUDEP (n = 4). Incidence of SUDEP was 0.6 per 100 000 person-years for the general population, and higher among men. The estimated incidence of SUDEP in the epilepsy population was 1.3 per 1000 person-years. SUDEP accounted for 0.1% of all deaths in Iceland during the study period. SIGNIFICANCE: SUDEP is an important cause of death in working-age people. This study provides the incidence of SUDEP in an unselected population of an entire country. The SUDEP incidence in the epilepsy population is comparable to that of previous studies.en_US
dc.description.sponsorshipHelga Jonsdottir and Sigurlidi Kristjansson Memorial Fund Landspitali Research Funden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.urlhttps://onlinelibrary.wiley.com/doi/full/10.1111/epi.16349en_US
dc.subjectSUDEPen_US
dc.subjectepidemiologyen_US
dc.subjectepilepsyen_US
dc.subjectincidenceen_US
dc.subjectpopulation-baseden_US
dc.subjectFlogaveikien_US
dc.subjectDánarmeinen_US
dc.subject.meshEpilepsyen_US
dc.subject.meshMortalityen_US
dc.titleSudden unexpected death in epilepsy. A nationwide population-based study.en_US
dc.typeArticleen_US
dc.contributor.department1 Department of Neurology, Landspitali University Hospital, Reykjavik, Iceland. 2 Department of Neurology, Odense University Hospital, Odense, Denmark. 3 Department of Neurology, Karolinska University Hospital, Stockholm, Sweden. 4 School of Medicine, University of Iceland, Reykjavik, Iceland.en_US
dc.identifier.journalEpilepsiaen_US
dc.rights.accessLandspitali Access - LSH-aðganguren_US
dc.departmentcodeNEU12
dc.source.journaltitleEpilepsia


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