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dc.contributor.authorBjörnsson, Einar S
dc.date.accessioned2020-01-10T11:24:17Z
dc.date.available2020-01-10T11:24:17Z
dc.date.issued2019-10-28
dc.date.submitted2020-01
dc.identifier.citationBjörnsson ES. Epidemiology, Predisposing Factors, and Outcomes of Drug-Induced Liver Injury. Clin Liver Dis. 2020;24(1):1–10. doi:10.1016/j.cld.2019.08.002en_US
dc.identifier.pmid31753242
dc.identifier.doi10.1016/j.cld.2019.08.002
dc.identifier.urihttp://hdl.handle.net/2336/621267
dc.descriptionTo access publisher's full text version of this article click on the hyperlink belowen_US
dc.description.abstractIdiosyncratic drug-induced liver injury (DILI) is an underreported and underestimated adverse drug reaction. A recent population-based study found a crude incidence of approximately 19 cases per 100,000 a year. Amoxicillin-clavulanate continues to be the most commonly implicated agent in most Western countries, reported to occur in approximately 1 of 2300 users. In patients with drug-induced autoimmune hepatitis, liver tests often do not normalize with cessation of the drugs and require corticosteroids. DILI associated with jaundice can lead to death from liver failure or require liver transplantation in at least 10% of cases.en_US
dc.language.isoenen_US
dc.publisherW B SAUNDERS CO-ELSEVIER INCen_US
dc.relation.urlhttps://www.sciencedirect.com/science/article/abs/pii/S1089326119300522?via%3Dihuben_US
dc.rightsCopyright © 2019 Elsevier Inc. All rights reserved.
dc.subjectDrug-induced liver injuryen_US
dc.subjectEpidemiologyen_US
dc.subjectPrognosisen_US
dc.subjectRisk factorsen_US
dc.subjectLifrarsjúkdómaren_US
dc.subjectLifrarskaðien_US
dc.subjectAukaverkanir lyfjaen_US
dc.subject.meshChemical and Drug Induced Liver Injuryen_US
dc.titleEpidemiology, Predisposing Factors, and Outcomes of Drug-Induced Liver Injury.en_US
dc.typeArticleen_US
dc.typeOtheren_US
dc.identifier.eissn1557-8224
dc.contributor.department1Department of Internal Medicine, Faculty of Medicine, Division of Gastroenterology and Hepatology, The National University Hospital of Iceland, University of Iceland, Hringbraut, Reykjavík 101, Iceland. Electronic address: einarsb@landspitali.is.en_US
dc.identifier.journalClinics in Liver Diseaseen_US
dc.rights.accessClosed - Lokaðen_US
dc.departmentcodeGAS12
dc.source.journaltitleClinics in liver disease
dc.source.volume24
dc.source.issue1
dc.source.beginpage1
dc.source.endpage10
dc.source.countryUnited States


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