The significance of bicuspid aortic valve after surgery for acute type A aortic dissection.
| dc.contributor.author | Mennander, Ari | |
| dc.contributor.author | Olsson, Christian | |
| dc.contributor.author | Jeppsson, Anders | |
| dc.contributor.author | Geirsson, Arnar | |
| dc.contributor.author | Hjortdal, Vibeke | |
| dc.contributor.author | Hansson, Emma C | |
| dc.contributor.author | Jarvela, Kati | |
| dc.contributor.author | Nozohoor, Shahab | |
| dc.contributor.author | Gunn, Jarmo | |
| dc.contributor.author | Ahlsson, Anders | |
| dc.contributor.author | Gudbjartsson, Tomas | |
| dc.date.accessioned | 2020-04-01T14:49:34Z | |
| dc.date.available | 2020-04-01T14:49:34Z | |
| dc.date.issued | 2019-03-21 | |
| dc.date.submitted | 2020-03 | |
| dc.identifier.citation | Mennander A, Olsson C, Jeppsson A, et al. The significance of bicuspid aortic valve after surgery for acute type A aortic dissection. J Thorac Cardiovasc Surg. 2020;159(3):760–767.e3. doi:10.1016/j.jtcvs.2019.03.012 | en_US |
| dc.identifier.pmid | 31005301 | |
| dc.identifier.doi | 10.1016/j.jtcvs.2019.03.012 | |
| dc.identifier.uri | http://hdl.handle.net/2336/621342 | |
| dc.description | To access publisher's full text version of this article click on the hyperlink below | en_US |
| dc.description.abstract | Objective: Decision-making concerning the extent of the repair of acute type A aortic dissection (ATAAD) includes functional and anatomical assessment of the aortic valve. We hypothesized that bicuspid aortic valve (BAV) does not impact outcome after surgery for ATAAD. We therefore evaluated the outcome after ATAAD surgery in relation to the presence of BAV, acute aortic regurgitation (AR), and surgical approach, using the Nordic Consortium for Acute Type A Aortic Dissection database. Methods: Eight participating Nordic centers collected data from 1122 patients undergoing ATAAD surgery during the years 2005 to 2014. Early complications, reoperations and survival were compared between patients with BAV and tricuspid aortic valves (TAV) before and after propensity score matching for sex, age, AR, organ malperfusion, hemodynamic instability, and site of the tear. Mean follow-up (range) for patients with TAV and BAV was 3.1 years (0-10.4 years) and 3.2 years (0-9.0 years), respectively. Results: Altogether, 65 (5.8%) of the patients had BAV. Root replacement was more frequently performed in the BAV as compared with the TAV group (60% vs 23%, P < .001). Survival, however, did not differ significantly between patients with BAV or TAV, either before (P = .230) or after propensity score-matching (P = .812). Even so, in cohort as a whole, patients presenting with AR had less favorable survival. Conclusions: Early and mid-term survival did not differ significantly between patients with BAV and TAV. | en_US |
| dc.description.sponsorship | Competitive State Research Financing of the Expert Responsibility area of Tampere University Hospital Mats Kleberg Foundation, Stockholm, Sweden | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | Mosby-Elsevier | en_US |
| dc.relation.url | https://www.sciencedirect.com/science/article/pii/S0022522319306804?via%3Dihub | en_US |
| dc.rights | Copyright © 2019 The American Association for Thoracic Surgery. Published by Elsevier Inc. All rights reserved. | |
| dc.subject | acute aortic valve regurgitation | en_US |
| dc.subject | acute type A aortic dissection | en_US |
| dc.subject | bicuspid aortic valve | en_US |
| dc.subject.mesh | Aortic Valve | en_US |
| dc.subject.mesh | Thoracic Surgical Procedures | en_US |
| dc.title | The significance of bicuspid aortic valve after surgery for acute type A aortic dissection. | en_US |
| dc.type | Article | en_US |
| dc.type | Other | en_US |
| dc.identifier.eissn | 1097-685X | |
| dc.contributor.department | 1Tampere University Heart Hospital and Tampere University, Tampere, Finland. Electronic address: ari.mennander@sydansairaala.fi. 2Karolinska University Hospital, Stockholm, Sweden. 3Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Cardiothoracic Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden. 4Landspitali University Hospital, Faculty of Medicine University of Iceland, Reykjavik, Iceland. 5Aarhus University Hospital, Aarhus, Denmark. 6Tampere University Heart Hospital and Tampere University, Tampere, Finland. 7Department of Cardiothoracic Surgery, Skane University Hospital, Clinical Sciences, Lund University, Lund, Sweden. 8Turku University Hospital, Turku, Finland. 9Orebro University Hospital, Orebro, Sweden. | en_US |
| dc.identifier.journal | The Journal of thoracic and cardiovascular surgery | en_US |
| dc.rights.access | National Consortium - Landsaðgangur | en_US |
| dc.departmentcode | ||
| dc.departmentcode | TAS12 | |
| dc.source.journaltitle | The Journal of thoracic and cardiovascular surgery | |
| dc.source.volume | 159 | |
| dc.source.issue | 3 | |
| dc.source.beginpage | 760 | |
| dc.source.endpage | 767.e3 | |
| dc.source.country | United States |
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Recombinant factor VIIa use in acute type A aortic dissection repair: A multicenter propensity-score-matched report from the Nordic Consortium for Acute Type A Aortic Dissection.Surgery for acute type A aortic dissection (ATAAD) is often complicated by excessive bleeding. Recombinant factor VIIa (rFVIIa) effectively treats refractory bleeding associated with ATAAD surgery; however, adverse effects of rFVIIa in these patients have not been fully assessed. Here we evaluated rFVIIa treatment in ATAAD surgery using the Nordic Consortium for Acute Type A Aortic Dissection (NORCAAD) database.
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