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Femoral nerve blocks for the treatment of acute pre-hospital pain: A systematic review with meta-analysis.

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Authors
Raatiniemi, Lasse
Magnusson, Vidar
Hyldmo, Per K
Friesgaard, Kristian D
Kongstad, Poul
Kurola, Jouni
Larsen, Robert
Rehn, Marius
Rognås, Leif
Sandberg, Mårten
Vist, Gunn E
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Issue Date
2020-04-09

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Citation
Raatiniemi L, Magnusson V, Hyldmo PK, et al. Femoral nerve blocks for the treatment of acute pre-hospital pain: A systematic review with meta-analysis [published online ahead of print, 2020 Apr 9]. Acta Anaesthesiol Scand. 2020;10.1111/aas.13600. doi:10.1111/aas.13600
Abstract
Background: Pain management is one of the most important interventions in the emergency medical services. The femoral nerve block (FNB) is, among other things, indicated for pre- and post-operative pain management for patients with femoral fractures but its role in the pre-hospital setting has not been determined. The aim of this review was to assess the effect and safety of the FNB in comparison to other forms of analgesia (or no treatment) for managing acute lower extremity pain in adult patients in the pre-hospital setting. Methods: A systematic review (PROSPERO registration (CRD42018114399)) was conducted. The Cochrane and GRADE methods were used to assess outcomes. Two authors independently reviewed each study for eligibility, extracted the data and performed risk of bias assessments. Results: Four studies with a total of 252 patients were included. Two RCTs (114 patients) showed that FNB may reduce pain more effectively than metamizole (mean difference 32 mm on a 100 mm VAS (95% CI 24 to 40)). One RCT (48 patients) compared the FNB with lidocaine and magnesium sulphate to FNB with lidocaine alone and was only included here for information regarding adverse effects. One case series included 90 patients. Few adverse events were reported in the included studies. The certainty of evidence was very low. We found no studies comparing FNB to inhaled analgesics, opioids or ketamine. Conclusions: Evidence regarding the effectiveness and adverse effects of pre-hospital FNB is limited. Studies comparing pre-hospital FNB to inhaled analgesics, opioids or ketamine are lacking.
Description
Oulu University Hospital
Additional Links
https://onlinelibrary.wiley.com/doi/full/10.1111/aas.13600
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© 2020 The Acta Anaesthesiologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.
ae974a485f413a2113503eed53cd6c53
10.1111/aas.13600
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English Journal Articles (Peer Reviewed)

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