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dc.contributor.authorRaatiniemi, Lasse
dc.contributor.authorMagnusson, Vidar
dc.contributor.authorHyldmo, Per K
dc.contributor.authorFriesgaard, Kristian D
dc.contributor.authorKongstad, Poul
dc.contributor.authorKurola, Jouni
dc.contributor.authorLarsen, Robert
dc.contributor.authorRehn, Marius
dc.contributor.authorRognås, Leif
dc.contributor.authorSandberg, Mårten
dc.contributor.authorVist, Gunn E
dc.date.accessioned2020-05-13T14:04:18Z
dc.date.available2020-05-13T14:04:18Z
dc.date.issued2020-04-09
dc.date.submitted2020-05
dc.identifier.citationRaatiniemi L, Magnusson V, Hyldmo PK, et al. Femoral nerve blocks for the treatment of acute pre-hospital pain: A systematic review with meta-analysis [published online ahead of print, 2020 Apr 9]. Acta Anaesthesiol Scand. 2020;10.1111/aas.13600. doi:10.1111/aas.13600en_US
dc.identifier.pmid32270488
dc.identifier.doi10.1111/aas.13600
dc.identifier.urihttp://hdl.handle.net/2336/621394
dc.descriptionOulu University Hospitalen_US
dc.description.abstractBackground: Pain management is one of the most important interventions in the emergency medical services. The femoral nerve block (FNB) is, among other things, indicated for pre- and post-operative pain management for patients with femoral fractures but its role in the pre-hospital setting has not been determined. The aim of this review was to assess the effect and safety of the FNB in comparison to other forms of analgesia (or no treatment) for managing acute lower extremity pain in adult patients in the pre-hospital setting. Methods: A systematic review (PROSPERO registration (CRD42018114399)) was conducted. The Cochrane and GRADE methods were used to assess outcomes. Two authors independently reviewed each study for eligibility, extracted the data and performed risk of bias assessments. Results: Four studies with a total of 252 patients were included. Two RCTs (114 patients) showed that FNB may reduce pain more effectively than metamizole (mean difference 32 mm on a 100 mm VAS (95% CI 24 to 40)). One RCT (48 patients) compared the FNB with lidocaine and magnesium sulphate to FNB with lidocaine alone and was only included here for information regarding adverse effects. One case series included 90 patients. Few adverse events were reported in the included studies. The certainty of evidence was very low. We found no studies comparing FNB to inhaled analgesics, opioids or ketamine. Conclusions: Evidence regarding the effectiveness and adverse effects of pre-hospital FNB is limited. Studies comparing pre-hospital FNB to inhaled analgesics, opioids or ketamine are lacking.en_US
dc.description.sponsorshipOulu University Hospitalen_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.urlhttps://onlinelibrary.wiley.com/doi/full/10.1111/aas.13600en_US
dc.rights© 2020 The Acta Anaesthesiologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.
dc.subjectDeyfingaren_US
dc.subjectBráðadeildiren_US
dc.subject.meshAnalgesiaen_US
dc.subject.meshPain Managementen_US
dc.subject.meshEmergency Service, Hospitalen_US
dc.titleFemoral nerve blocks for the treatment of acute pre-hospital pain: A systematic review with meta-analysis.en_US
dc.typeArticleen_US
dc.typeOtheren_US
dc.identifier.eissn1399-6576
dc.contributor.department1Centre for Prehospital Emergency Care, Oulu University Hospital, Oulu, Finland. 2Anaesthesia Research group, MRC, Oulu University Hospital and University of Oulu, Oulu, Finland. 3Prehospital section and Department of Anaesthesia, Landspitalinn University Hospital, Reykjavik, Iceland. 4Faculty of Health Sciences, University of Stavanger, Stavanger, Norway. 5Department of Research, Norwegian Air Ambulance Foundation, Oslo, Norway. 6Trauma Unit, Sørlandet Hospital, Kristiansand, Norway. 7Research Department, Prehospital Emergency Medical Service, Central Denmark Region, Århus, Denmark. 8Department of Anaesthesiology, Regional Hospital of Horsens, Horsens, Denmark. 9Department of Prehospital Care and Disaster Medicine, Region of Skåne, Lund, Sweden. 10Centre for Prehospital Emergency Medicine, Kuopio University Hospital and University of Eastern Finland, Kuopio, Finland. 11Department of Clinical and Experimental Medicine, Faculty of Medicine and Health Sciences, University of Linköping, Linköping, Sweden. 12Division of Prehospital Services, Air Ambulance Department, Oslo University Hospital, Oslo, Norway. 13Danish Air Ambulance, Aarhus, Denmark. 14Department of Anaesthesiology, Aarhus University Hospital, Aarhus, Denmark. 15Department of Clinical Medicine, Aarhus University, Aarhus, Denmark. 16Faculty of Medicine, University of Oslo, Oslo, Norway. 17Division of Health Services, Norwegian Institute of Public Health, Oslo, Norway.en_US
dc.identifier.journalActa anaesthesiologica Scandinavicaen_US
dc.rights.accessNational Consortium - Landsaðganguren_US
dc.departmentcodeAAA12
dc.source.journaltitleActa anaesthesiologica Scandinavica
dc.source.countryEngland


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