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dc.contributor.authorMarcu, Sara
dc.contributor.authorPegolo, Elena
dc.contributor.authorÍvarsson, Eysteinn
dc.contributor.authorJónasson, Aron D
dc.contributor.authorJónasson, Viktor D
dc.contributor.authorAubonnet, Romain
dc.contributor.authorGargiulo, Paolo
dc.contributor.authorBanea, Ovidiu C
dc.date.accessioned2020-10-19T15:26:30Z
dc.date.available2020-10-19T15:26:30Z
dc.date.issued2020-04-01
dc.date.submitted2020-10
dc.identifier.citationMarcu S, Pegolo E, Ívarsson E, Jónasson AD, Jónasson VD, Aubonnet R, Gargiulo P, Banea OC. Using high density EEG to assess TMS treatment in patients with schizophrenia. Eur J Transl Myol. 2020 Apr 1;30(1):8903. doi: 10.4081/ejtm.2019.8903. PMID: 32499897; PMCID: PMC7254438.en_US
dc.identifier.issn2037-7452
dc.identifier.pmid32499897
dc.identifier.doi10.4081/ejtm.2019.8903
dc.identifier.urihttp://hdl.handle.net/2336/621544
dc.descriptionTo access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Downloaden_US
dc.description.abstractWe present preliminary results from the ongoing study entitled "Icelandic AVH-TMS" which aim is to study the effectiveness of repetitive transcranial magnetic stimulation (rTMS) treatment for patients with schizophrenia and with persistent auditory verbal hallucinations (AVH) using symptoms and psychometric scales and high-density EEG system (256 channels). The aim of the present work was to describe cortical topography of the auditory evoked responses like P50 and N100-P300 complex in healthy participants and patients with schizophrenia and to define a robust methodology of signal quantification using dense-array EEG. Preliminary data is shown for three healthy participants and three patients in baseline conditions and for two patients we show the results recorded before and after 10 days rTMS treatment. Our results show differences in sensory gating (P50 suppresion) and a stronger N100-P300 response to rare audio stimulus after the treatment. Moreover we show the value of assessing brain electrical activity from high-density EEG (256 channels) analyzing the results in different regions of interest. However, it is premature and hazardous to assume that rTMS treatment effectiveness in patients with AVH can be assessed using P50 suppression ratio. Keywords: P300; P50; Transcranial magnetic stimulation; high density EEG; schizophrenia.en_US
dc.language.isoenen_US
dc.publisherPAGEPRESS PUBLen_US
dc.relation.urlhttps://www.pagepressjournals.org/index.php/bam/article/view/8903en_US
dc.relation.urlhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254438/en_US
dc.subjectP300en_US
dc.subjectP50en_US
dc.subjectTranscranial magnetic stimulationen_US
dc.subjecthigh density EEGen_US
dc.subjectschizophreniaen_US
dc.subjectHeilariten_US
dc.subjectGeðklofien_US
dc.subject.meshElectrocorticographyen_US
dc.subject.meshTranscranial Magnetic Stimulationen_US
dc.subject.meshSchizophreniaen_US
dc.titleUsing high density EEG to assess TMS treatment in patients with schizophrenia.en_US
dc.typeArticleen_US
dc.contributor.department1Reykjavik University, School of Science and Engineering, Biomedical Engineering, Reykjavik, Iceland. 2Department of Information Engineering, University of Padova, Italy. 3Clinical Neurophysiology Unit, Neurology Department, National University Hospital of Iceland. 4Psychiatric Department, National University Hospital of Iceland.en_US
dc.identifier.journalEuropean journal of translational myologyen_US
dc.rights.accessOpen Access - Opinn aðganguren_US
dc.departmentcodeRES12
dc.departmentcodePSC12
dc.departmentcodeNAF12
dc.departmentcodeNEU12
dc.source.journaltitleEuropean journal of translational myology
dc.source.volume30
dc.source.issue1
dc.source.beginpage8903
dc.source.endpage
refterms.dateFOA2020-10-19T15:26:31Z
dc.source.countryItaly


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