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Heilkenni skammvinns höfuðverkjar með brottfallseinkennum og eitilfrumuhækkun í mænuvökva · Tvö sjúkratilfelli og yfirlit ·

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Authors
Helgi Kristjánsson
Ólafur Árni Sveinsson
Issue Date
2021-02

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Other Titles
Syndrome of transient headache and neurologic deficits with cerebrospinal fluid lymphocytosis – two cases and review
Citation
Helgi Kristjánsson, Ólafur Árni Sveinsson. Heilkenni skammvinns höfuðverkjar með brottfallseinkennum og eitilfrumuhækkun í mænuvökva: tvö sjúkratilfelli og yfirlit. Læknablaðið. 2021; 107(2): 67-73.
Abstract
Hér er lýst tveimur tilfellum af HaNDL (Headache with Neurological Deficits and cerebrospinal fluid Lymphocytosis) eða heilkenni skammvinns höfuðverkjar með brottfallseinkennum og eitilfrumuhækkun í mænuvökva. Fyrra tilfellið var þrítugur maður sem fékk endurtekin köst með höfuðverk, helftareinkennum og mikilli óáttun. Hið síðara var 41 árs maður sem fékk höfuðverk, skyndilegt málstol og hægri helftareinkenni. Í báðum tilfellum var töluverð hækkun á eitilfrumum í mænuvökva. Leit að sýkingarvöldum var neikvæð og segulómskoðanir af höfði sýndu engar meinsemdir. Einkenni gengu að fullu til baka hjá báðum sjúklingum. Orsök HaNDL er óþekkt en sumir telja ástandið orsakast af bólguviðbrögðum í kjölfar veirusýkingar. Horfur eru góðar og sjúklingar verða einkennalausir á einni til þremur vikum. Mikilvægt er að útiloka alvarlegri orsakir eins og heilaslag, innanskúmsblæðingu eða sýkingar í miðtaugakerfi.
Here we describe two cases of HaNDL (Headache with Neurological Deficits and cerebrospinal fluid Lymphocytosis). A thirty year old man with episodes of headache with lateralizing symptoms and confusion and a 41 year old man with headache, aphasia and right hemiparesis. Symptoms resolved completely in both patients. Considerable cerebrospinal fluid lymphocytosis was present but no signs of CNS infection and MRIs of the brain were normal. Although the cause of HaNDL is unknown, it is thought to be triggered by a viral infection by some. The prognosis is excellent and symptoms normally resolve within 1-3 weeks. It is important to rule out more serious etiologies like stroke, subarachnoid hemorrhage or central nervous system infections.
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https://www.laeknabladid.is/tolublod/2021/02/nr/7608
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Icelandic Journal Articles (Peer Reviewed)

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