Mild Stage 1 post-operative acute kidney injury: association with chronic kidney disease and long-term survival.
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Authors
Long, Thorir EinarssonHelgason, Dadi
Helgadottir, Solveig
Sigurdsson, Gisli Heimir
Palsson, Runolfur
Sigurdsson, Martin Ingi
Indridason, Olafur Skuli
Issue Date
2020-02-10
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Long TE, Helgason D, Helgadottir S, Sigurdsson GH, Palsson R, Sigurdsson MI, Indridason OS. Mild Stage 1 post-operative acute kidney injury: association with chronic kidney disease and long-term survival. Clin Kidney J. 2020 Feb 10;14(1):237-244. doi: 10.1093/ckj/sfz197.Abstract
Pre- and post-operative SCr values were available for 47 333 (42%) surgeries. Of those, 1161 (2.4%) had mild Stage 1 AKI and 2355 (5%) more severe forms of AKI. Mild Stage 1 AKI was associated with both incident CKD and progression of pre-existing CKD (P < 0.001). After exclusion of post-operative deaths within 30 days, mild Stage 1 AKI was not associated with worse 1-year survival in patients with preserved kidney function (94% versus 94%, P = 0.660), and same was true for patients with pre-operative CKD (83% versus 82%, P = 0.870) compared with their matched individuals. Conclusions. Mild Stage 1 AKI is associated with development and progression of CKD, but not with inferior 1-year survival. These findings support the inclusion of a small absolute increase in SCr in the definition of AKI.Description
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https://academic.oup.com/ckj/article/14/1/237/5733044https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857788/
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© The Author(s) 2020. Published by Oxford University Press on behalf of ERA-EDTA.ae974a485f413a2113503eed53cd6c53
10.1093/ckj/sfz197
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