Lower consumption of cow milk protein A1 beta-casein at 2 years of age, rather than consumption among 11- to 14-year-old adolescents, may explain the lower incidence of type 1 diabetes in Iceland than in Scandinavia
Average rating
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Star rating
Your vote was cast
Thank you for your feedback
Thank you for your feedback
Issue Date
2006-05-01
Metadata
Show full item recordCitation
Ann. Nutr. Metab. 2006, 50(3):177-83Abstract
AIM: To compare the consumption of the cow milk proteins A1 and B beta-casein among children and adolescents in Iceland and Scandinavia (Norway, Denmark, Sweden and Finland) as this might explain the lower incidence of type 1 diabetes (per 100,000/year, 0-14 years) in Iceland. METHODS: The consumption of A1 beta-casein in each country among 2- and 11- to 14-year-old children was calculated from results on food intake and on cow milk protein concentration. The consumption values were then compared and evaluated against the incidence of type 1 diabetes. RESULTS: There was a significant difference between the consumption of A1 (p = 0.034) as well as the sum of A1 and B (p = 0.021) beta-casein in Iceland and Scandinavia for 2-year-old children. In the same age group, consumption of A1 beta-casein correlated with the incidence of type 1 diabetes in the countries (r = 0.9; p = 0.037). No significant difference in consumption of A1 or the sum of A1 and B beta-casein was found for 11- to 14-year-old adolescents. CONCLUSION: This study supports that lower consumption of A1 beta-casein might be related to the lower incidence of type 1 diabetes in Iceland than in Scandinavia. Additionally it indicates that consumption in young childhood might be of more importance for the development of the disease incidence than consumption in adolescence.Description
To access publisher full text version of this article. Please click on the hyperlink in Additional Links fieldAdditional Links
http://content.karger.com/ProdukteDB/produkte.asp?Aktion=ShowPDF&ArtikelNr=90738&Ausgabe=231622&ProduktNr=223977&filename=90738.pdfae974a485f413a2113503eed53cd6c53
10.1159/000090738
Scopus Count
Collections
Related articles
- Ischaemic heart disease, Type 1 diabetes, and cow milk A1 beta-casein.
- Authors: Laugesen M, Elliott R
- Issue date: 2003 Jan 24
- Variation in consumption of cow milk proteins and lower incidence of Type 1 diabetes in Iceland vs the other 4 Nordic countries.
- Authors: Birgisdottir BE, Hill JP, Harris DP, Thorsdottir I
- Issue date: 2002 Aug
- Type I (insulin-dependent) diabetes mellitus and cow milk: casein variant consumption.
- Authors: Elliott RB, Harris DP, Hill JP, Bibby NJ, Wasmuth HE
- Issue date: 1999 Mar
- Different beta-casein fractions in Icelandic versus Scandinavian cow's milk may influence diabetogenicity of cow's milk in infancy and explain low incidence of insulin-dependent diabetes mellitus in Iceland.
- Authors: Thorsdottir I, Birgisdottir BE, Johannsdottir IM, Harris DP, Hill J, Steingrimsdottir L, Thorsson AV
- Issue date: 2000 Oct
- The A2 milk case: a critical review.
- Authors: Truswell AS
- Issue date: 2005 May