Show simple item record

dc.contributor.authorGeirsson, G
dc.contributor.authorLindström, S
dc.contributor.authorFall, M
dc.date.accessioned2009-04-20T13:25:39Z
dc.date.available2009-04-20T13:25:39Z
dc.date.issued1999-12-01
dc.date.submitted2009-04-20
dc.identifier.citationJ. Urol. 1999, 162(6):1890-6en
dc.identifier.issn0022-5347
dc.identifier.pmid10569531
dc.identifier.urihttp://hdl.handle.net/2336/65495
dc.descriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links fielden
dc.description.abstractPURPOSE: We review the physiology of bladder cooling response in experimental animals and humans, and present its clinical usefulness. MATERIALS AND METHODS: We describe experimental studies of the bladder cooling response, and more recent clinical retrospective and prospective studies of the bladder cooling test in adults and children. RESULTS: Studies indicate the existence of a segmental spinal bladder cooling reflex that originates from specific cold receptors in the bladder and urethral walls supplied by unmyelinated C-afferents. The reflex is positive in neurologically normal infants and children until about age 4 years. It becomes negative with further maturation of the nervous system but may be unmasked by pathological processes that disturb the descending neuronal control of normal voiding. A positive test in a patient with an overactive bladder requires further neurourological evaluation. CONCLUSIONS: The bladder cooling response originates from cold receptors within the walls of the lower urinary tract. The cooling response represents a neonatal reflex that may be unmasked by central neuropathology, analogous to the appearance of the Basbinki sign in pyramidal tract lesions. The bladder cooling test is a simple and valuable tool to support the diagnosis of neurourological disorders.
dc.language.isoenen
dc.publisherElsevieren
dc.relation.urlhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&NEWS=N&PAGE=fulltext&AN=00005392-199912000-00004&LSLINK=80&D=ovften
dc.subject.meshAdulten
dc.subject.meshAnimalsen
dc.subject.meshCapsaicinen
dc.subject.meshChilden
dc.subject.meshCold Temperatureen
dc.subject.meshHumansen
dc.subject.meshInfanten
dc.subject.meshMentholen
dc.subject.meshMuscle, Smoothen
dc.subject.meshPhysical Stimulationen
dc.subject.meshReflexen
dc.subject.meshUrinary Bladderen
dc.subject.meshUrinary Bladder Diseasesen
dc.titleThe bladder cooling reflex and the use of cooling as stimulus to the lower urinary tract.en
dc.typeArticleen
dc.contributor.departmentDepartment of Urology, Sjúkrahús Reykjavikur, Reykjavik, Iceland.en
dc.identifier.journalJournal of urologyen
html.description.abstractPURPOSE: We review the physiology of bladder cooling response in experimental animals and humans, and present its clinical usefulness. MATERIALS AND METHODS: We describe experimental studies of the bladder cooling response, and more recent clinical retrospective and prospective studies of the bladder cooling test in adults and children. RESULTS: Studies indicate the existence of a segmental spinal bladder cooling reflex that originates from specific cold receptors in the bladder and urethral walls supplied by unmyelinated C-afferents. The reflex is positive in neurologically normal infants and children until about age 4 years. It becomes negative with further maturation of the nervous system but may be unmasked by pathological processes that disturb the descending neuronal control of normal voiding. A positive test in a patient with an overactive bladder requires further neurourological evaluation. CONCLUSIONS: The bladder cooling response originates from cold receptors within the walls of the lower urinary tract. The cooling response represents a neonatal reflex that may be unmasked by central neuropathology, analogous to the appearance of the Basbinki sign in pyramidal tract lesions. The bladder cooling test is a simple and valuable tool to support the diagnosis of neurourological disorders.


This item appears in the following Collection(s)

Show simple item record