COMT val(158)met genotype and smooth pursuit eye movements in schizophrenia
| dc.contributor.author | Haraldsson, H M | |
| dc.contributor.author | Ettinger, U | |
| dc.contributor.author | Magnusdottir, B B | |
| dc.contributor.author | Sigmundsson, T | |
| dc.contributor.author | Sigurdsson, E | |
| dc.contributor.author | Ingason, A | |
| dc.contributor.author | Petursson, H | |
| dc.date.accessioned | 2009-09-08T14:34:49Z | |
| dc.date.available | 2009-09-08T14:34:49Z | |
| dc.date.issued | 2009-09-30 | |
| dc.date.submitted | 2009-09-08 | |
| dc.identifier.citation | Psychiatry Res. 2009, 169(2):173-175 | en |
| dc.identifier.issn | 0165-1781 | |
| dc.identifier.pmid | 19647329 | |
| dc.identifier.doi | 10.1016/j.psychres.2008.10.003 | |
| dc.identifier.uri | http://hdl.handle.net/2336/80374 | |
| dc.description | To access publisher full text version of this article. Please click on the hyperlink in Additional Links field | en |
| dc.description.abstract | The association between the catechol-O-methyltransferase (COMT) val(158)met polymorphism (rs4680) and smooth pursuit eye movements (SPEM) was investigated in 110 schizophrenia patients and 96 controls. Patients had lower steady-state pursuit gain and made more frequent saccades than controls. Genotype was not associated with schizophrenia or SPEM, in either group or the combined sample. SPEM deficits in schizophrenia appear to be determined by genotypes other than rs4680, although the study may have lacked power to detect small effects. | |
| dc.language | ENG | |
| dc.language.iso | n/a | en |
| dc.publisher | Elsevier/North-Holland Biomedical Press | en |
| dc.relation.url | http://dx.doi.org/10.1016/j.psychres.2008.10.003 | en |
| dc.title | COMT val(158)met genotype and smooth pursuit eye movements in schizophrenia | n/a |
| dc.type | Article | en |
| dc.contributor.department | Division of Psychiatry, Landspitali-University Hospital, Reykjavik, Iceland. | en |
| dc.identifier.journal | Psychiatry research | en |
| html.description.abstract | The association between the catechol-O-methyltransferase (COMT) val(158)met polymorphism (rs4680) and smooth pursuit eye movements (SPEM) was investigated in 110 schizophrenia patients and 96 controls. Patients had lower steady-state pursuit gain and made more frequent saccades than controls. Genotype was not associated with schizophrenia or SPEM, in either group or the combined sample. SPEM deficits in schizophrenia appear to be determined by genotypes other than rs4680, although the study may have lacked power to detect small effects. |
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