Epidemiology of the optic nerve grey crescent in the Reykjavik Eye Study.
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Your vote was cast
Thank you for your feedback
Thank you for your feedback
MetadataShow full item record
CitationBr J Ophthalmol. 2005, 89(1):36-9
AbstractAIM: To establish the epidemiology of the grey crescent in a white population within the age range most susceptible to glaucoma. METHODS: Bruce Shields was first to use this term to describe a localised, physiological pigmentation of the optic nerve neuroretinal rim tissue that is distinct from peripapillary pigmentation. An experienced glaucomatologist (KFD) evaluated stereofundus photographs of the participants of the Reykjavik Eye Study (RES)-a random sample from the national population census including people 50 years and older. 1012 right eyes could be evaluated for grey crescent. RESULTS: The prevalence of grey crescent in the right eyes was 22.0% (95% CI 10 to 25). It was more commonly found in women (27.0%: 95% CI 23 to 30) than in men (17.0%: 95% CI 14 to 21), and was most often located temporally (36.9%), 360 degrees (15.9%), or nasally (15.4%). The spherical equivalent was +1.30 dioptres (D) for those with and +0.80 D for those without grey crescent (p = 0.002), respectively. Vertical optic disc diameters were 0.203 v 0.195 units (p<0.001). There was no difference in the prevalence of grey crescent in glaucomatous or non-glaucomatous eyes (OR = 1.05, 95% CI 0.49 to 2.26). The prevalence of a grey crescent was inversely related to the prevalence of peripapillary atrophy (p = 0.001). CONCLUSIONS: The grey crescent needs to be recognised as a physiological variant in order to avoid falsely labelling eyes as having glaucomatous optic nerve damage.
DescriptionTo access publisher full text version of this article. Please click on the hyperlink in Additional Links field
- Gray optic disc crescent: influence of ethnicity in a glaucoma population.
- Authors: Higginbotham L, Shafranov G, Shields MB
- Issue date: 2007 Sep
- Characteristics and appearance of the normal optic nerve head in 6-year-old children.
- Authors: Samarawickrama C, Pai A, Tariq Y, Healey PR, Wong TY, Mitchell P
- Issue date: 2012 Jan
- High myopia and glaucoma susceptibility the Beijing Eye Study.
- Authors: Xu L, Wang Y, Wang S, Wang Y, Jonas JB
- Issue date: 2007 Feb
- Increased disk size in glaucomatous eyes vs normal eyes in the Reykjavik eye study.
- Authors: Wang L, Damji KF, Munger R, Jonasson F, Arnarsson A, Sasaki H, Sasaki K
- Issue date: 2003 Feb
- Small neuroretinal rim and large parapapillary atrophy as predictive factors for progression of glaucomatous optic neuropathy.
- Authors: Jonas JB, Martus P, Budde WM, Jünemann A, Hayler J
- Issue date: 2002 Aug