Reiterssjúkdómur : sjúklingar vistaðir á Landakotsspítala 1970 til 1984

Abstract

To examine whether long term antibiotic treatment is effective in shortening or preventing attacks of Reiters disease, a retrospective study was undertaken on 35 patients, (32 males, 3 females) who all fulfilled the ARA criteria for Reiters disease and had been treated at St. Joseph's Hospital, Reykjavik in the years 1970-1984. They were followed up to the end of 1988. Patients with enteropathic conditions were excluded. All but three got 14 days initial treatment with Erythromycin, Sulfadimethoxin or Tetracyclin. Seventeen patients got treatment for more than one year, 10 for 3-6 months, 20 with Trimethoprim-sulfa. Seven with Sulfadimethoxin. Eight patients had no long term treatment. Eighty five per cent of the long term treatment group had attacks lasting six months or less versus 75% in the short term treatment group. Two attacks or less were observed in 75% of those treated for one year or more. In 40% of the 3-6 months treatment group and in 38% of those not having received long term treatment. Of the remaining patients, all had more than two attacks, some more than five with more or less chronic symptoms.

Óvissa hefur ríkt um hvort langtíma sýklalyfjagjöf hafi áhrif á gang Reiterssjúkdóms. Til að forvitnast um þetta voru sjúkraskrár allra sjúklinga með Reiterssjúkdóm, sem innlagðir höfðu verið á St. Jósefsspítalann, Landakoti árin 1970-1984, athugaðar. Haft var samband við þá sjúklinga sem mögulegt var, og sjúkrasaga fengin til ársloka 1988. Leitast var við að fá upplýsingar um það hversu lengi sjúkdómur hafði staðið, virkni hans og tegund meðferðar.